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Evaluation and management of congenital bleeding disorders. [Review] - 2014

Available online from MWHC library: 1996 - present

Patients presenting to the emergency department with acute bleeding and a history of clotting or platelet disorder present a unique challenge to the emergency physician. The severity of bleeding presentation is based on mechanism as well as factor levels: patients with factor levels greater than 5% can respond to most minor hemostatic challenges, whereas those with factor levels less than 1% bleed with minor trauma or even spontaneously. Treatment should be initiated in consultation with the patient's hematologist using medications and specific factor replacement, except in rare, life-threatening, resource-poor situations, when cryoprecipitate or activated prothrombin complex may be considerations. Copyright 2014 Elsevier Inc. All rights reserved.


English

ISSN: 0733-8627

Subjects--Topical Terms:
*Blood Coagulation Disorders, Inherited/di [Diagnosis]
*Blood Coagulation Factors/tu [Therapeutic Use]
*Hemorrhage/et [Etiology]
Blood Coagulation Disorders, Inherited/dt [Drug Therapy]
Blood Coagulation Disorders, Inherited/pp [Physiopathology]
Emergency Service, Hospital
Humans

Subjects--Geographic Terms:
MedStar Washington Hospital Center

Index Terms--Occupation:
Emergency Medicine

Index Terms--Function:
Journal Article
Review