The Effect of Maternal Obesity on Oxytocin Requirements to Achieve Vaginal Delivery.

The Effect of Maternal Obesity on Oxytocin Requirements to Achieve Vaginal Delivery. - 2020

CONCLUSION: Obese women are more likely to require oxytocin rates more than 20 mU/min, higher doses of oxytocin, and greater duration of oxytocin exposure to achieve a vaginal delivery. Copyright Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA. OBJECTIVE: Our objective was to determine if obese women are more likely to require oxytocin rates > 20 mU/min to achieve vaginal delivery, compared with normal weight women. RESULTS: There were 4,284 births included in the analysis. Thirty-three per cent of deliveries were among women classified as overweight (body mass index [BMI] 25-29.9 kg/m2) and 58% were among women classified as obese (BMI >30.0 kg/m2), 12% were classified as class III obesity (BMI >40 kg/m2). Overall 110 (2.6%) women required an oxytocin rate of >20 mU/min. Doses of oxytocin >20 mU/min for women in the overweight, class I obesity, and class II obesity groups were 2.6, 1.9, and 1.6%, respectively. Deliveries among women with class III obesity had a significantly longer duration of oxytocin exposure (10.7 hours) compared with the normal weight group (8.2 hours, p < 0.001), and had a higher maximum rate of oxytocin compared (10 mU/min) to normal weight women (8 mU/min, p < 0.001). STUDY DESIGN: This is a retrospective cohort study of deliveries at the MedStar Washington Hospital Center and MedStar Georgetown University Hospital.


English

0735-1631

10.1055/s-0039-1694982 [doi]


*Labor, Induced
*Obesity, Maternal
*Oxytocics/ad [Administration & Dosage]
*Oxytocin/ad [Administration & Dosage]
Adolescent
Adult
Body Mass Index
Delivery, Obstetric
Dose-Response Relationship, Drug
Female
Humans
Middle Aged
Overweight
Pregnancy
Retrospective Studies
Young Adult


MedStar Washington Hospital Center


Obstetrics and Gynecology/Maternal-Fetal Medicine


Journal Article

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