Trends of Hospitalizations in the United States from 2000 to 2012 of Patients >60 Years With Aortic Valve Disease.

Trends of Hospitalizations in the United States from 2000 to 2012 of Patients >60 Years With Aortic Valve Disease.

Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006

1,909 to 8,172 (p <0.001). The total annual cost for AVD hospitalization in the United States increased from In recent years, there has been an increased emphasis on the diagnosis and treatment of valvular heart disease and, in particular, aortic stenosis. This has been driven in part by the development of innovative therapeutic options and by an aging patient population. We hypothesized an increase in the number of hospitalizations and the economic burden associated with aortic valve disease (AVD). Using Nationwide Inpatient Sample from 2000 to 2012, AVD-related hospitalizations were identified using International Classification of Diseases, Ninth Revision, Clinical Modification, code 424.1, as the principal discharge diagnosis. Overall AVD hospitalizations increased by 59% from 2000 to 2012. This increase was most significant in patients >80 years and those with higher burden of co-morbidities. The most frequent coexisting conditions were hypertension, heart failure, renal failure, anemia, and diabetes. Overall inhospital mortality of patients hospitalized for AVD was 3.8%, which significantly decreased from 4.5% in 2000 to 3.5% in 2012 (p <0.001). The largest decrease in mortality was seen in the subgroup of patients who had heart failure (62% reduction), higher burden of co-morbidities (58% reduction), and who were >80 years (53% reduction). There was a substantial increase in the cost of hospitalization in the last decade from


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0002-9149


*Heart Defects, Congenital/di [Diagnosis]
*Heart Defects, Congenital/th [Therapy]
*Heart Valve Diseases/di [Diagnosis]
*Heart Valve Diseases/th [Therapy]
*Hospital Mortality/td [Trends]
*Hospitalization/td [Trends]
Aged
Aged, 80 and over
Aortic Valve
Aortic Valve Stenosis/di [Diagnosis]
Aortic Valve Stenosis/th [Therapy]
Cost of Illness
Female
Heart Defects, Congenital/ec [Economics]
Heart Defects, Congenital/mo [Mortality]
Heart Valve Diseases/ec [Economics]
Heart Valve Diseases/mo [Mortality]
Hospitalization/ec [Economics]
Humans
Male
Middle Aged
Risk Assessment
Risk Factors
United States


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