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Thoracoscopic Resection of Multiple Mullerian Cysts. - 2015

Available online from MWHC library: 1995 - present, Available in print through MWHC library:1999-2007

Mullerian cysts in the mediastinum were first described by Hattori in 2005 [1]. We report the first known case of multiple mullerian cysts in the thorax in a 35-year-old woman with cough and an abnormal chest roentgenogram. Multiple bilateral cysts were resected thoracoscopically. Histologic examination showed benign ciliated tubal epithelium that stained positive with immunohistochemical stains for estrogen receptor (ER), cancer antigen 125 (CA-125), Wilms' tumor protein 1 (WT-1), and paired box gene 8 (PAX8), confirming mullerian origin. We also review the embryogenesis and pathologic characteristics of mullerian cysts and the rare occurrence of their migration to the thorax.Copyright © 2015 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.


English

ISSN: 0003-4975

Subjects--Topical Terms:
*Mediastinal Cyst/su [Surgery]
*Mullerian Ducts
*Thoracoscopy
Adult
CA-125 Antigen/me [Metabolism]
Epithelium/pa [Pathology]
Female
Humans
Immunohistochemistry
Mediastinal Cyst/me [Metabolism]
Mediastinal Cyst/pa [Pathology]
Mullerian Ducts/pa [Pathology]
Paired Box Transcription Factors/me [Metabolism]
Receptors, Estrogen/me [Metabolism]
WT1 Proteins/me [Metabolism]

Subjects--Geographic Terms:
MedStar Washington Hospital Center

Index Terms--Occupation:
Surgery/Thoracic Surgery

Index Terms--Function:
Case Reports
Journal Article