Long-term Metformin Use and Vitamin B12 Deficiency in the Diabetes Prevention Program Outcomes Study.
Long-term Metformin Use and Vitamin B12 Deficiency in the Diabetes Prevention Program Outcomes Study.
- 2016
Available online through MWHC library: 1999- June 2013, Available in print through MWHC library: 1999 - 2006
Participants from DPP/DPPOS were assigned to placebo (n=1082) or metformin (n=1073) for 3.2 years, followed by metformin in the metformin group for 9 years. Metformin use was associated with increased risk of vitamin B12 deficiency.
English
0021-972X
*Anemia/ci [Chemically Induced]
*Diabetes Mellitus, Type 2/pc [Prevention & Control]
*Hypoglycemic Agents/ae [Adverse Effects]
*Metformin/ae [Adverse Effects]
*Vitamin B 12 Deficiency/ci [Chemically Induced]
Adult
Aged
Female
Homocysteine/bl [Blood]
Humans
Hypoglycemic Agents/tu [Therapeutic Use]
Male
Metformin/tu [Therapeutic Use]
Middle Aged
Vitamin B 12/bl [Blood]
MedStar Health Research Institute
Journal Article
Multicenter Study
Randomized Controlled Trial
Available online through MWHC library: 1999- June 2013, Available in print through MWHC library: 1999 - 2006
Participants from DPP/DPPOS were assigned to placebo (n=1082) or metformin (n=1073) for 3.2 years, followed by metformin in the metformin group for 9 years. Metformin use was associated with increased risk of vitamin B12 deficiency.
English
0021-972X
*Anemia/ci [Chemically Induced]
*Diabetes Mellitus, Type 2/pc [Prevention & Control]
*Hypoglycemic Agents/ae [Adverse Effects]
*Metformin/ae [Adverse Effects]
*Vitamin B 12 Deficiency/ci [Chemically Induced]
Adult
Aged
Female
Homocysteine/bl [Blood]
Humans
Hypoglycemic Agents/tu [Therapeutic Use]
Male
Metformin/tu [Therapeutic Use]
Middle Aged
Vitamin B 12/bl [Blood]
MedStar Health Research Institute
Journal Article
Multicenter Study
Randomized Controlled Trial