Ultrasound-guided foam sclerotherapy as a therapeutic modality in venous ulceration. [Review]
Ultrasound-guided foam sclerotherapy as a therapeutic modality in venous ulceration. [Review]
- 2022
CONCLUSION: A prospective, trial is warranted in order to determine the true merits of UGFS in the setting of venous ulceration. Copyright © 2021 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved. METHODS: The MEDLINE, CENTRAL and Embase databases were used to search for relevant studies using the terms ' (sclerotherapy AND ulcer) OR (vein AND ulcer) OR (sclerotherapy AND vein)'. Heterogeneity between studies was quantified using the I2 statistic. A random effects model was used to calculate risk ratios where substantial heterogeneity was found. OBJECTIVES: The objective of this systematic review and meta-analysis was to evaluate rates of ulcer healing following ultrasound-guided foam sclerotherapy (UGFS). RESULTS: The initial search yielded 8266 articles. 8 studies were included in the qualitative synthesis and 3 in the meta-analysis. Superior complete ulcer healing rates were noted in patients treated with foam sclerotherapy versus compression therapy alone (pooled OR 6.41, 95% CI = 0.3-148.2, p = 0.246, random effects method). A marked degree of heterogeneity was observed between studies (I2 = 81%).
English
1479-666X
10.1016/j.surge.2021.08.008 [doi] S1479-666X(21)00141-4 [pii]
*Varicose Ulcer
*Varicose Veins
Humans
Prospective Studies
Recurrence
Saphenous Vein
Sclerotherapy/ae [Adverse Effects]
Sclerotherapy/mt [Methods]
Treatment Outcome
Ulcer/et [Etiology]
Ultrasonography, Interventional
Varicose Ulcer/dg [Diagnostic Imaging]
Varicose Ulcer/et [Etiology]
Varicose Ulcer/th [Therapy]
Varicose Veins/et [Etiology]
MedStar Heart & Vascular Institute
Journal Article
Meta-Analysis
Review
Systematic Review
CONCLUSION: A prospective, trial is warranted in order to determine the true merits of UGFS in the setting of venous ulceration. Copyright © 2021 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved. METHODS: The MEDLINE, CENTRAL and Embase databases were used to search for relevant studies using the terms ' (sclerotherapy AND ulcer) OR (vein AND ulcer) OR (sclerotherapy AND vein)'. Heterogeneity between studies was quantified using the I2 statistic. A random effects model was used to calculate risk ratios where substantial heterogeneity was found. OBJECTIVES: The objective of this systematic review and meta-analysis was to evaluate rates of ulcer healing following ultrasound-guided foam sclerotherapy (UGFS). RESULTS: The initial search yielded 8266 articles. 8 studies were included in the qualitative synthesis and 3 in the meta-analysis. Superior complete ulcer healing rates were noted in patients treated with foam sclerotherapy versus compression therapy alone (pooled OR 6.41, 95% CI = 0.3-148.2, p = 0.246, random effects method). A marked degree of heterogeneity was observed between studies (I2 = 81%).
English
1479-666X
10.1016/j.surge.2021.08.008 [doi] S1479-666X(21)00141-4 [pii]
*Varicose Ulcer
*Varicose Veins
Humans
Prospective Studies
Recurrence
Saphenous Vein
Sclerotherapy/ae [Adverse Effects]
Sclerotherapy/mt [Methods]
Treatment Outcome
Ulcer/et [Etiology]
Ultrasonography, Interventional
Varicose Ulcer/dg [Diagnostic Imaging]
Varicose Ulcer/et [Etiology]
Varicose Ulcer/th [Therapy]
Varicose Veins/et [Etiology]
MedStar Heart & Vascular Institute
Journal Article
Meta-Analysis
Review
Systematic Review