Intravascular large B-cell lymphoma presenting as multiple stroke: A case report.
Intravascular large B-cell lymphoma presenting as multiple stroke: A case report.
- 2018
Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006
CASE PRESENTATION: We report an interesting case of IVLBCL presenting as bilateral strokes. The diagnosis was made by a random skin biopsy, which confirmed IVLBCL. The patient was treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP).Neurological symptoms improved with R-CHOP. Repeat magnetic resonance imaging (MRI) of the brain showed improvement of the prior lesions. CONCLUSION: IVLBCL is an aggressive disease with high mortality. Timely diagnosis and treatment can be lifesaving. INTRODUCTION: Intravascular large B-cell lymphoma (IVLBCL) is an uncommon disease with a poor prognosis if not diagnosed early. It can present with central nervous system (CNS) manifestations. The diagnosis of IVCBCL is difficult to make given its varied clinical manifestations and the lack of a specific diagnostic modality.
English
0025-7974
00005792-201810120-00087 [pii] 10.1097/MD.0000000000012793 [doi]
*Lymphoma, Large B-Cell, Diffuse/di [Diagnosis]
*Lymphoma, Large B-Cell, Diffuse/pa [Pathology]
*Stroke/di [Diagnosis]
*Stroke/pa [Pathology]
*Vascular Neoplasms/di [Diagnosis]
*Vascular Neoplasms/pa [Pathology]
Antibodies, Monoclonal, Murine-Derived
Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Diagnosis, Differential
Doxorubicin
Female
Humans
Lymphoma, Large B-Cell, Diffuse/dt [Drug Therapy]
Middle Aged
Prednisone
Vascular Neoplasms/dt [Drug Therapy]
Vincristine
Medstar Franklin Square Medical Center
Pulmonary and Critical Care Medicine
Journal Article
Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006
CASE PRESENTATION: We report an interesting case of IVLBCL presenting as bilateral strokes. The diagnosis was made by a random skin biopsy, which confirmed IVLBCL. The patient was treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP).Neurological symptoms improved with R-CHOP. Repeat magnetic resonance imaging (MRI) of the brain showed improvement of the prior lesions. CONCLUSION: IVLBCL is an aggressive disease with high mortality. Timely diagnosis and treatment can be lifesaving. INTRODUCTION: Intravascular large B-cell lymphoma (IVLBCL) is an uncommon disease with a poor prognosis if not diagnosed early. It can present with central nervous system (CNS) manifestations. The diagnosis of IVCBCL is difficult to make given its varied clinical manifestations and the lack of a specific diagnostic modality.
English
0025-7974
00005792-201810120-00087 [pii] 10.1097/MD.0000000000012793 [doi]
*Lymphoma, Large B-Cell, Diffuse/di [Diagnosis]
*Lymphoma, Large B-Cell, Diffuse/pa [Pathology]
*Stroke/di [Diagnosis]
*Stroke/pa [Pathology]
*Vascular Neoplasms/di [Diagnosis]
*Vascular Neoplasms/pa [Pathology]
Antibodies, Monoclonal, Murine-Derived
Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Diagnosis, Differential
Doxorubicin
Female
Humans
Lymphoma, Large B-Cell, Diffuse/dt [Drug Therapy]
Middle Aged
Prednisone
Vascular Neoplasms/dt [Drug Therapy]
Vincristine
Medstar Franklin Square Medical Center
Pulmonary and Critical Care Medicine
Journal Article