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Intralesional Cidofovir for Treatment of Acyclovir-Resistant Laryngeal Herpes Manifesting as Supraglottic Mass. - 2018

Available online from MWHC library: 1998 - 2008, Available in print through MWHC library: 1999 - 2008

CASE PRESENTATION:: We report a case of bulky, obstructive supraglottic and glottic herpes virus laryngitis that presented with dysphonia, dysphagia, and airway complaints resistant to acyclovir analogues that was treated effectively with intralesional cidofovir injection. CONCLUSIONS:: Our promising initial response suggests a potential novel treatment for this unusual condition. INTRODUCTION:: Laryngopharyngeal herpes simplex virus infection is rare and presents typically in the supraglottis. Findings on presentation can range from small mucosal lesions to fungating obstructive masses mimicking neoplasm. Laryngopharyngeal herpes is a medically treated disease. METHODS:: Individual case with treatment adapted from other case report. OBJECTIVES:: Identify potential treatment in cases that are refractory to antiviral medications.


English

ISSN: 0003-4894

Standard No.: 10.1177/0003489418818579 [doi]

Subjects--Topical Terms:
IN PROCESS -- NOT YET INDEXED

Subjects--Geographic Terms:
MedStar Washington Hospital Center

Index Terms--Occupation:
Medicine/Infectious Diseases

Index Terms--Function:
Journal Article