Uncontrolled recurrent myasthenia gravis exacerbations secondary to chronic gabapentin use.
Uncontrolled recurrent myasthenia gravis exacerbations secondary to chronic gabapentin use.
- 2019
Gabapentin is an anticonvulsant medication that reduces synaptic transmission by decreasing presynaptic voltage-gated Ca2+ and Na+ channels. It is approved to treat focal seizures but also used to treat post-herpetic and neuropathic pain. Although uncommon, there have been three reported cases of myasthenia gravis exacerbation associated with gabapentin in the literature. We present a patient with uncontrolled recurrent myasthenia gravis exacerbations secondary to chronic gabapentin use and provide a review for the three published cases.
English
2000-9666
10.1080/20009666.2019.1643220 [doi] 1643220 [pii] PMC6735302 [pmc]
IN PROCESS -- NOT YET INDEXED
MedStar Harbor Hospital
Medicine
Case Reports
Gabapentin is an anticonvulsant medication that reduces synaptic transmission by decreasing presynaptic voltage-gated Ca2+ and Na+ channels. It is approved to treat focal seizures but also used to treat post-herpetic and neuropathic pain. Although uncommon, there have been three reported cases of myasthenia gravis exacerbation associated with gabapentin in the literature. We present a patient with uncontrolled recurrent myasthenia gravis exacerbations secondary to chronic gabapentin use and provide a review for the three published cases.
English
2000-9666
10.1080/20009666.2019.1643220 [doi] 1643220 [pii] PMC6735302 [pmc]
IN PROCESS -- NOT YET INDEXED
MedStar Harbor Hospital
Medicine
Case Reports