A Gut Feeling: Acute Liver Failure - An Unusual Manifestation of Malignant Catatonia.
A Gut Feeling: Acute Liver Failure - An Unusual Manifestation of Malignant Catatonia.
- 2021
We present a rare case in which malignant catatonia led to acute liver failure (ALF). A 19-year-old male was admitted for psychosis and developed ALF with a peak aspartate aminotransferase and alanine aminotransferase of 5,728 U/L and 7,735 U/L, respectively, and a peak international normalized ratio of 7.1. Liver biopsy showed significant confluent necrosis involving >70% of the liver tissue. He was listed for a liver transplant but was ultimately taken off of because of significant improvement with treatment by N-acetylcysteine infusion. Through our research, we found that symptoms of hepatitis can be seen with psychotic disorders, but ALF is rare. Copyright (c) 2021, Kiparizoska et al.
English
10.7759/cureus.15242 [doi] PMC8232982 [pmc]
IN PROCESS -- NOT YET INDEXED
MedStar Washington Hospital Center
Internal Medicine Residency
Case Reports
We present a rare case in which malignant catatonia led to acute liver failure (ALF). A 19-year-old male was admitted for psychosis and developed ALF with a peak aspartate aminotransferase and alanine aminotransferase of 5,728 U/L and 7,735 U/L, respectively, and a peak international normalized ratio of 7.1. Liver biopsy showed significant confluent necrosis involving >70% of the liver tissue. He was listed for a liver transplant but was ultimately taken off of because of significant improvement with treatment by N-acetylcysteine infusion. Through our research, we found that symptoms of hepatitis can be seen with psychotic disorders, but ALF is rare. Copyright (c) 2021, Kiparizoska et al.
English
10.7759/cureus.15242 [doi] PMC8232982 [pmc]
IN PROCESS -- NOT YET INDEXED
MedStar Washington Hospital Center
Internal Medicine Residency
Case Reports