MARC details
| 000 -LEADER |
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| fixed length control field |
03303nam a22006017a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
210719s20212021 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
1083-7159 |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1002/onco.13846 [doi] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
34097758 |
| 245 ## - TITLE STATEMENT |
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| Title |
Single-Center Analysis of Characteristics and Outcomes of De Novo, Concurrent, and Transformed Diffuse Large B-Cell Lymphoma. |
| 251 ## - Source |
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| Source |
Oncologist. 26(9):e1660-e1663, 2021 09. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
Oncologist. 26(9):e1660-e1663, 2021 09. |
| 252 ## - Abbreviated Source |
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| Former abbreviated source |
Oncologist. 2021 Jun 07 |
| 253 ## - Journal Name |
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| Journal name |
The oncologist |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2021 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2022 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Publication date |
2021 Jun 07 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
aheadofprint |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
ppublish |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2021-07-19 |
| 268 ## - Previous citation |
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| -- |
Oncologist. 2021 Jun 07 |
| 269 ## - Original dates |
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| Original fiscal year |
FY2021 |
| 501 ## - WITH NOTE |
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| Local holdings |
Available online from MWHC library: 1996 - present |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Outcomes of diffuse large B-cell lymphoma (DLBCL), either concurrent with or transformed from indolent lymphoma, treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone are described in retrospective studies. The efficacy of other regimens in transformed or concurrent DLBCL is largely unknown. In this single-center retrospective study, we present characteristics of concurrent and transformed DLBCL and outcomes after dose-adjusted etoposide, vincristine, cyclophosphamide, prednisone, and doxorubicin with rituximab (DA-EPOCH-R) comparative with de novo DLBCL. Of 170 patients with DLBCL, 136 were de novo, 17 were concurrent, and 17 were transformed. Transformed DLBCL had significantly lower complete response rates and progression-free survival (PFS) but similar overall survival (OS) compared with de novo counterpart. There was no significant difference between de novo and concurrent DLBCL regarding response rates, PFS, and OS. DA-EPOCH-R was associated with inferior OS. Thus, intensified treatment with DA-EPOCH-R might not improve outcomes of transformed DLBCL. Copyright (c) 2021 AlphaMed Press. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Antineoplastic Combined Chemotherapy Protocols |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Lymphoma, Large B-Cell, Diffuse |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Antineoplastic Combined Chemotherapy Protocols/tu [Therapeutic Use] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Cyclophosphamide/tu [Therapeutic Use] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Doxorubicin/tu [Therapeutic Use] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Humans |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Lymphoma, Large B-Cell, Diffuse/dt [Drug Therapy] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Prednisone/tu [Therapeutic Use] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Prognosis |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Retrospective Studies |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Rituximab/tu [Therapeutic Use] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Vincristine/tu [Therapeutic Use] |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Washington Hospital Center |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
Washington Cancer Institute |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Hematology/Oncology Fellowship |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Internal Medicine Residency |
| 657 ## - INDEX TERM--FUNCTION |
|---|
| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Baez-Sosa, Valentina |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Chaturvedi, Mansi |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Desai, Sanjal |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Hameed, Rumaisa |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Shenoy, Aarthi G |
| 790 ## - Authors |
|---|
| All authors |
Baez-Sosa V, Chaturvedi M, Desai S, Hameed R, Shenoy AG |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1002/onco.13846">https://dx.doi.org/10.1002/onco.13846</a> |
| Public note |
https://dx.doi.org/10.1002/onco.13846 |
| 858 ## - ORCID |
|---|
| ORCID text |
Desai, Sanjal |
| Orcid |
<a href="https://orcid.org/0000-0002-7892-2625">https://orcid.org/0000-0002-7892-2625</a> |
| Name |
https://orcid.org/0000-0002-7892-2625 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Journal Article |
| Item type description |
Article |
