MARC details
| 000 -LEADER |
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| fixed length control field |
02470nam a22003377a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
211101s20212021 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
2090-6390 |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
34471548 |
| 245 ## - TITLE STATEMENT |
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| Title |
Suspected Sugammadex Hypersensitivity following Repeated Administration in the Setting of Multiple Flap Takebacks in a Brief Timespan. |
| 251 ## - Source |
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| Source |
Case Reports in Anesthesiology. 2021:5716159, 2021. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
Case Rep Anesthesiol. 2021:5716159, 2021. |
| 253 ## - Journal Name |
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| Journal name |
Case reports in anesthesiology |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2021 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2022 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
epublish |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2021-11-01 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Sugammadex hypersensitivity is an uncommon event that typically occurs at higher doses. We report a case of suspected sugammadex hypersensitivity in a patient who developed hypoxia and bronchospasm following three administrations of the standard 2 mg/kg doses of sugammadex within 26 hours due to flap takebacks. Hypersensitivity to sugammadex was not initially suspected given that the patient had previous exposures. Diagnoses of pneumothorax, hemothorax, mucus plug, and tracheal tube malposition were immediately ruled out. Furthermore, the onset of hypoxia with sudden loss of tidal volume, development of high peak airway pressures, and temporal correlation with sugammadex administration all supported bronchospasm secondary to a hypersensitivity reaction. Sugammadex is a useful agent for neuromuscular blockade reversal; however, it is critical to carefully examine all adverse reactions. This case report highlights the importance of considering hypersensitivity reactions in the setting of repeat sugammadex administrations in a limited timeframe, such as in free flap reconstruction requiring multiple takebacks to the operating room in the setting of flap compromise. Copyright (c) 2021 Elizabeth G. Zolper et al. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Washington Hospital Center |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Plastic Surgery Residency |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Surgery/Plastic Surgery |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Case Reports |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Fan, Kenneth L |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Zolper, Elizabeth G |
| 790 ## - Authors |
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| All authors |
Bekeny JC, Dekker PK, Fan KL, Kim AH, Kim KG, Song DH, Zolper EG |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1155/2021/5716159">https://dx.doi.org/10.1155/2021/5716159</a> |
| Public note |
https://dx.doi.org/10.1155/2021/5716159 |
| 858 ## - ORCID |
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| ORCID text |
Fan, Kenneth L |
| Orcid |
<a href="https://orcid.org/0000-0001-5951-5576">https://orcid.org/0000-0001-5951-5576</a> |
| Name |
https://orcid.org/0000-0001-5951-5576 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
