Brain Metastases From Differentiated Thyroid Carcinoma: Prevalence, Current Therapies, and Outcomes. (Record no. 11153)

MARC details
000 -LEADER
fixed length control field 03991nam a22005897a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 190314s20192019 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 2472-1972
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1210/js.2018-00241 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code js_201800241 [pii]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code PMC6348752 [pmc]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 30706042
245 ## - TITLE STATEMENT
Title Brain Metastases From Differentiated Thyroid Carcinoma: Prevalence, Current Therapies, and Outcomes.
251 ## - Source
Source Journal of the Endocrine Society. 3(2):359-371, 2019 Feb 01.
252 ## - Abbreviated Source
Abbreviated source J. endocr. soc.. 3(2):359-371, 2019 Feb 01.
253 ## - Journal Name
Journal name Journal of the Endocrine Society
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2019
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2019
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status epublish
266 ## - Date added to catalog
Date added to catalog 2019-03-14
520 ## - SUMMARY, ETC.
Abstract Background and Objective: The brain is an unusual site for distant metastases of differentiated thyroid carcinoma (DTC). The aim of this study was to document the prevalence of brain metastases from DTC at our institutions and to analyze the current therapies and the outcomes of these patients.
520 ## - SUMMARY, ETC.
Abstract Conclusion: The prevalence of brain metastases of DTC in our institutions was 0.3% over 15 years. The median survival time after diagnosis of brain metastases was 19 months. In our study population, the use of TKI improved the survival rates.
520 ## - SUMMARY, ETC.
Abstract Methods: We performed a retrospective chart review of patients with DTC and secondary neoplasia of the brain.
520 ## - SUMMARY, ETC.
Abstract Results: From 2002 to 2016, 9514 cases of thyroid cancer were evaluated across our institutions and 24 patients met our inclusion criteria, corresponding to a prevalence of 0.3% of patients with DTC. Fourteen (58.3%) were female and 10 (41.7%) were male. Fifteen patients had papillary thyroid cancer (PTC) (62.5%). Brain metastases were diagnosed 0 to 37 years (mean +/- SD, 10.6 +/- 10.4 years) after the initial diagnosis of thyroid cancer. Patients undergoing surgery had a median survival time longer than those that did not undergo surgery (27.3 months vs 6.8 months; P = 0.15). Patients who underwent stereotactic radiosurgery (SRS) had a median survival time longer than those that did not receive SRS (52.5 months vs 6.7 months; P = 0.11). Twelve patients (50%) were treated with tyrosine kinase inhibitors (TKIs), and they had a better survival than those who have not used a TKI (median survival time, 27.2 months vs 4.7 months; P < 0.05).
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Health Research Institute
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Institution MedStar Washington Hospital Center
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Department Medicine/Endocrinology
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Department Medicine/Internal Medicine
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Department Medicine/Nuclear Medicine
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Department Neurosurgery
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Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Aulisi, Edward
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Local Authors Burman, Kenneth D
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Deeb, Hala
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Gomes-Lima, Cristiane J
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Hritani, Rama
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Local Authors Jonklaas, Jacqueline
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Local Authors Mete, Mihriye
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Punukollu, Sree
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Rao, Sarika N
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Van Nostrand, Douglas
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Wartofsky, Leonard
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Local Authors Wu, Di
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Zeymo, Alexander
790 ## - Authors
All authors Aulisi EF, Burman KD, Deeb H, Gomes-Lima CJ, Hritani R, Jonklaas J, Mete M, Punukollu S, Rao SN, Van Nostrand D, Wartofsky L, Wu D, Zeymo A
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1210/js.2018-00241">https://dx.doi.org/10.1210/js.2018-00241</a>
Public note https://dx.doi.org/10.1210/js.2018-00241
858 ## - ORCID
ORCID text Gomes-Lima, Cristiane J
-- Wu, Di
Orcid <a href="https://orcid.org/0000-0001-7684-8268">https://orcid.org/0000-0001-7684-8268</a>
-- <a href="https://orcid.org/0000-0003-1567-1977">https://orcid.org/0000-0003-1567-1977</a>
Name https://orcid.org/0000-0001-7684-8268
-- https://orcid.org/0000-0003-1567-1977
-- https://orcid.org/0000-0001-7684-8268
-- https://orcid.org/0000-0003-1567-1977
858 ## - ORCID
ORCID text Gomes-Lima, Cristiane J
-- Wu, Di
Orcid <a href="https://orcid.org/0000-0001-7684-8268">https://orcid.org/0000-0001-7684-8268</a>
-- <a href="https://orcid.org/0000-0003-1567-1977">https://orcid.org/0000-0003-1567-1977</a>
Name https://orcid.org/0000-0001-7684-8268
-- https://orcid.org/0000-0003-1567-1977
-- https://orcid.org/0000-0001-7684-8268
-- https://orcid.org/0000-0003-1567-1977
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 03/14/2019   30706042 30706042 03/14/2019 03/14/2019 Journal Article

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