MARC details
000 -LEADER |
fixed length control field |
03991nam a22005897a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
190314s20192019 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
2472-1972 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1210/js.2018-00241 [doi] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
js_201800241 [pii] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
PMC6348752 [pmc] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
30706042 |
245 ## - TITLE STATEMENT |
Title |
Brain Metastases From Differentiated Thyroid Carcinoma: Prevalence, Current Therapies, and Outcomes. |
251 ## - Source |
Source |
Journal of the Endocrine Society. 3(2):359-371, 2019 Feb 01. |
252 ## - Abbreviated Source |
Abbreviated source |
J. endocr. soc.. 3(2):359-371, 2019 Feb 01. |
253 ## - Journal Name |
Journal name |
Journal of the Endocrine Society |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2019 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2019 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
epublish |
266 ## - Date added to catalog |
Date added to catalog |
2019-03-14 |
520 ## - SUMMARY, ETC. |
Abstract |
Background and Objective: The brain is an unusual site for distant metastases of differentiated thyroid carcinoma (DTC). The aim of this study was to document the prevalence of brain metastases from DTC at our institutions and to analyze the current therapies and the outcomes of these patients. |
520 ## - SUMMARY, ETC. |
Abstract |
Conclusion: The prevalence of brain metastases of DTC in our institutions was 0.3% over 15 years. The median survival time after diagnosis of brain metastases was 19 months. In our study population, the use of TKI improved the survival rates. |
520 ## - SUMMARY, ETC. |
Abstract |
Methods: We performed a retrospective chart review of patients with DTC and secondary neoplasia of the brain. |
520 ## - SUMMARY, ETC. |
Abstract |
Results: From 2002 to 2016, 9514 cases of thyroid cancer were evaluated across our institutions and 24 patients met our inclusion criteria, corresponding to a prevalence of 0.3% of patients with DTC. Fourteen (58.3%) were female and 10 (41.7%) were male. Fifteen patients had papillary thyroid cancer (PTC) (62.5%). Brain metastases were diagnosed 0 to 37 years (mean +/- SD, 10.6 +/- 10.4 years) after the initial diagnosis of thyroid cancer. Patients undergoing surgery had a median survival time longer than those that did not undergo surgery (27.3 months vs 6.8 months; P = 0.15). Patients who underwent stereotactic radiosurgery (SRS) had a median survival time longer than those that did not receive SRS (52.5 months vs 6.7 months; P = 0.11). Twelve patients (50%) were treated with tyrosine kinase inhibitors (TKIs), and they had a better survival than those who have not used a TKI (median survival time, 27.2 months vs 4.7 months; P < 0.05). |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Health Research Institute |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Washington Hospital Center |
656 ## - INDEX TERM--OCCUPATION |
Department |
Medicine/Endocrinology |
656 ## - INDEX TERM--OCCUPATION |
Department |
Medicine/Internal Medicine |
656 ## - INDEX TERM--OCCUPATION |
Department |
Medicine/Nuclear Medicine |
656 ## - INDEX TERM--OCCUPATION |
Department |
Neurosurgery |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Aulisi, Edward |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Burman, Kenneth D |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Deeb, Hala |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Gomes-Lima, Cristiane J |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Hritani, Rama |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Jonklaas, Jacqueline |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Mete, Mihriye |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Punukollu, Sree |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Rao, Sarika N |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Van Nostrand, Douglas |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Wartofsky, Leonard |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Wu, Di |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Zeymo, Alexander |
790 ## - Authors |
All authors |
Aulisi EF, Burman KD, Deeb H, Gomes-Lima CJ, Hritani R, Jonklaas J, Mete M, Punukollu S, Rao SN, Van Nostrand D, Wartofsky L, Wu D, Zeymo A |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1210/js.2018-00241">https://dx.doi.org/10.1210/js.2018-00241</a> |
Public note |
https://dx.doi.org/10.1210/js.2018-00241 |
858 ## - ORCID |
ORCID text |
Gomes-Lima, Cristiane J |
-- |
Wu, Di |
Orcid |
<a href="https://orcid.org/0000-0001-7684-8268">https://orcid.org/0000-0001-7684-8268</a> |
-- |
<a href="https://orcid.org/0000-0003-1567-1977">https://orcid.org/0000-0003-1567-1977</a> |
Name |
https://orcid.org/0000-0001-7684-8268 |
-- |
https://orcid.org/0000-0003-1567-1977 |
-- |
https://orcid.org/0000-0001-7684-8268 |
-- |
https://orcid.org/0000-0003-1567-1977 |
858 ## - ORCID |
ORCID text |
Gomes-Lima, Cristiane J |
-- |
Wu, Di |
Orcid |
<a href="https://orcid.org/0000-0001-7684-8268">https://orcid.org/0000-0001-7684-8268</a> |
-- |
<a href="https://orcid.org/0000-0003-1567-1977">https://orcid.org/0000-0003-1567-1977</a> |
Name |
https://orcid.org/0000-0001-7684-8268 |
-- |
https://orcid.org/0000-0003-1567-1977 |
-- |
https://orcid.org/0000-0001-7684-8268 |
-- |
https://orcid.org/0000-0003-1567-1977 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |