MARC details
000 -LEADER |
fixed length control field |
05050nam a22007697a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
130912s20122012 xxu||||| |||| 00| 0 eng dOvid Technologies |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
0002-9149 |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
22112742 |
245 ## - TITLE STATEMENT |
Title |
Outcome of percutaneous coronary intervention utilizing drug-eluting stents in patients with reduced left ventricular ejection fraction. |
251 ## - Source |
Source |
American Journal of Cardiology. 109(3):344-51, 2012 Feb 1. |
252 ## - Abbreviated Source |
Abbreviated source |
Am J Cardiol. 109(3):344-51, 2012 Feb 1. |
253 ## - Journal Name |
Journal name |
The American journal of cardiology |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2012 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2012 |
266 ## - Date added to catalog |
Date added to catalog |
2013-09-17 |
501 ## - WITH NOTE |
Local holdings |
Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006 |
520 ## - SUMMARY, ETC. |
Abstract |
Ischemic cardiomyopathy with depressed left ventricular ejection fraction (LVEF) is predictive of death after percutaneous coronary intervention (PCI), but its association with stent thrombosis (ST) and the need for repeat revascularization is less clearly defined. In total 5,377 patients undergoing PCI were retrospectively evaluated. Multivariable Cox proportional hazards regression and competitive outcome analysis were employed. The primary end point was 1-year major adverse cardiac events (all-cause death, Q-wave myocardial infarction, ST, and target lesion revascularization [TLR]). Individual end points of ST and of TLR were also evaluated. Patients with normal LVEF (>50%) were compared to those with mild (41% to 50%), moderate (25% to 40%), and severe (<25%) decreases in LVEF. Patients with abnormal LVEF were older and more commonly diabetic and had renal insufficiency and heart failure syndrome (p <0.001 for all variables). These patients demonstrated more angiographically complex lesions and less frequently received a drug-eluting stent. The primary end point was significantly increased in patients with lower LVEF (9.7% for normal LVEF vs 20.6% for severely decreased LVEF, p <0.001). ST occurred more frequently in these patients (1.4% for normal LVEF vs 6% for severely decreased LVEF, p <0.001), but clinically driven TLR did not significantly 130912 across LVEF categories. After adjustment, only moderate and severe LVEF decreases (i.e., LVEF <=40%) demonstrated an association with major adverse cardiac events and with the individual outcome of ST. Subgroup analysis of patients receiving only a drug-eluting stent or a bare-metal stent demonstrated no statistically significant differences for the probability of ST. In conclusion, decreased LVEF is not associated with clinically driven TLR but does increase the risk of ST. Patients with LVEF <=40% appear to be at significantly higher risk for ST and therefore might benefit from interventional and pharmacologic strategies aimed at minimizing this risk. Copyright 2012 Elsevier Inc. All rights reserved. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Angioplasty, Balloon, Coronary/mt [Methods] |
9 (RLIN) |
952 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Drug-Eluting Stents |
9 (RLIN) |
525 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Myocardial Ischemia/su [Surgery] |
9 (RLIN) |
960 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Stroke Volume |
9 (RLIN) |
802 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Ventricular Dysfunction, Left/co [Complications] |
9 (RLIN) |
962 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Aged |
9 (RLIN) |
2 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Cause of Death/td [Trends] |
9 (RLIN) |
953 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Coronary Angiography |
9 (RLIN) |
90 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
District of Columbia/ep [Epidemiology] |
9 (RLIN) |
954 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Echocardiography |
9 (RLIN) |
955 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Electrocardiography |
9 (RLIN) |
495 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Female |
9 (RLIN) |
7 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Follow-Up Studies |
9 (RLIN) |
956 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Gated Blood-Pool Imaging |
9 (RLIN) |
957 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Humans |
9 (RLIN) |
11 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Male |
9 (RLIN) |
14 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Middle Aged |
9 (RLIN) |
15 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Myocardial Ischemia/co [Complications] |
9 (RLIN) |
958 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Myocardial Ischemia/mo [Mortality] |
9 (RLIN) |
959 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Prognosis |
9 (RLIN) |
280 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Retrospective Studies |
9 (RLIN) |
46 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Risk Factors |
9 (RLIN) |
311 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Survival Rate/td [Trends] |
9 (RLIN) |
961 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Treatment Outcome |
9 (RLIN) |
18 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Ventricular Dysfunction, Left/mo [Mortality] |
9 (RLIN) |
963 |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Ventricular Dysfunction, Left/pp [Physiopathology] |
9 (RLIN) |
964 |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Health Research Institute |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Heart & Vascular Institute |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Comparative Study |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Ben-Dor, Itsik |
9 (RLIN) |
22 |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Gaglia, Michael AJ |
9 (RLIN) |
951 |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Hauville, Camille |
9 (RLIN) |
532 |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Kent, Kenneth M |
9 (RLIN) |
135 |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Laynez-Carnicero, Ana |
9 (RLIN) |
897 |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Lindsay, Joseph |
9 (RLIN) |
137 |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Maluenda, Gabriel |
9 (RLIN) |
286 |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Pichard, Augusto D |
9 (RLIN) |
27 |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Sardi, Gabriel L |
9 (RLIN) |
138 |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Satler, Lowell F |
9 (RLIN) |
29 |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Suddath, William O |
9 (RLIN) |
139 |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Torguson, Rebecca |
9 (RLIN) |
140 |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Waksman, Ron |
9 (RLIN) |
30 |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Xue, Zhenyi |
9 (RLIN) |
141 |
790 ## - Authors |
All authors |
Ben-Dor I, Gaglia MA Jr, Hauville C, Kent KM, Laynez-Carnicero A, Lindsay J, Maluenda G, Pichard AD, Sardi GL, Satler LF, Suddath WO, Torguson R, Waksman R, Xue Z |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="http://dx.doi.org/10.1016/j.amjcard.2011.09.016">http://dx.doi.org/10.1016/j.amjcard.2011.09.016</a> |
Public note |
http://dx.doi.org/10.1016/j.amjcard.2011.09.016 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Source of classification or shelving scheme |
Other/Generic Classification Scheme |
Item type description |
Article |