Outcome of percutaneous coronary intervention utilizing drug-eluting stents in patients with reduced left ventricular ejection fraction. (Record no. 1244)

MARC details
000 -LEADER
fixed length control field 05050nam a22007697a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 130912s20122012 xxu||||| |||| 00| 0 eng dOvid Technologies
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0002-9149
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 22112742
245 ## - TITLE STATEMENT
Title Outcome of percutaneous coronary intervention utilizing drug-eluting stents in patients with reduced left ventricular ejection fraction.
251 ## - Source
Source American Journal of Cardiology. 109(3):344-51, 2012 Feb 1.
252 ## - Abbreviated Source
Abbreviated source Am J Cardiol. 109(3):344-51, 2012 Feb 1.
253 ## - Journal Name
Journal name The American journal of cardiology
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2012
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2012
266 ## - Date added to catalog
Date added to catalog 2013-09-17
501 ## - WITH NOTE
Local holdings Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006
520 ## - SUMMARY, ETC.
Abstract Ischemic cardiomyopathy with depressed left ventricular ejection fraction (LVEF) is predictive of death after percutaneous coronary intervention (PCI), but its association with stent thrombosis (ST) and the need for repeat revascularization is less clearly defined. In total 5,377 patients undergoing PCI were retrospectively evaluated. Multivariable Cox proportional hazards regression and competitive outcome analysis were employed. The primary end point was 1-year major adverse cardiac events (all-cause death, Q-wave myocardial infarction, ST, and target lesion revascularization [TLR]). Individual end points of ST and of TLR were also evaluated. Patients with normal LVEF (>50%) were compared to those with mild (41% to 50%), moderate (25% to 40%), and severe (<25%) decreases in LVEF. Patients with abnormal LVEF were older and more commonly diabetic and had renal insufficiency and heart failure syndrome (p <0.001 for all variables). These patients demonstrated more angiographically complex lesions and less frequently received a drug-eluting stent. The primary end point was significantly increased in patients with lower LVEF (9.7% for normal LVEF vs 20.6% for severely decreased LVEF, p <0.001). ST occurred more frequently in these patients (1.4% for normal LVEF vs 6% for severely decreased LVEF, p <0.001), but clinically driven TLR did not significantly 130912 across LVEF categories. After adjustment, only moderate and severe LVEF decreases (i.e., LVEF <=40%) demonstrated an association with major adverse cardiac events and with the individual outcome of ST. Subgroup analysis of patients receiving only a drug-eluting stent or a bare-metal stent demonstrated no statistically significant differences for the probability of ST. In conclusion, decreased LVEF is not associated with clinically driven TLR but does increase the risk of ST. Patients with LVEF <=40% appear to be at significantly higher risk for ST and therefore might benefit from interventional and pharmacologic strategies aimed at minimizing this risk. Copyright 2012 Elsevier Inc. All rights reserved.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Angioplasty, Balloon, Coronary/mt [Methods]
9 (RLIN) 952
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Drug-Eluting Stents
9 (RLIN) 525
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Myocardial Ischemia/su [Surgery]
9 (RLIN) 960
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Stroke Volume
9 (RLIN) 802
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Ventricular Dysfunction, Left/co [Complications]
9 (RLIN) 962
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aged
9 (RLIN) 2
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cause of Death/td [Trends]
9 (RLIN) 953
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Coronary Angiography
9 (RLIN) 90
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element District of Columbia/ep [Epidemiology]
9 (RLIN) 954
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Echocardiography
9 (RLIN) 955
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Electrocardiography
9 (RLIN) 495
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Female
9 (RLIN) 7
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Follow-Up Studies
9 (RLIN) 956
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Gated Blood-Pool Imaging
9 (RLIN) 957
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
9 (RLIN) 11
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Male
9 (RLIN) 14
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Middle Aged
9 (RLIN) 15
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Myocardial Ischemia/co [Complications]
9 (RLIN) 958
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Myocardial Ischemia/mo [Mortality]
9 (RLIN) 959
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Prognosis
9 (RLIN) 280
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Retrospective Studies
9 (RLIN) 46
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Risk Factors
9 (RLIN) 311
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Survival Rate/td [Trends]
9 (RLIN) 961
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Treatment Outcome
9 (RLIN) 18
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Ventricular Dysfunction, Left/mo [Mortality]
9 (RLIN) 963
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Ventricular Dysfunction, Left/pp [Physiopathology]
9 (RLIN) 964
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Health Research Institute
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Heart & Vascular Institute
657 ## - INDEX TERM--FUNCTION
Medline publication type Comparative Study
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Ben-Dor, Itsik
9 (RLIN) 22
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Gaglia, Michael AJ
9 (RLIN) 951
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Hauville, Camille
9 (RLIN) 532
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Kent, Kenneth M
9 (RLIN) 135
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Laynez-Carnicero, Ana
9 (RLIN) 897
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Lindsay, Joseph
9 (RLIN) 137
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Maluenda, Gabriel
9 (RLIN) 286
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Pichard, Augusto D
9 (RLIN) 27
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Sardi, Gabriel L
9 (RLIN) 138
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Satler, Lowell F
9 (RLIN) 29
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Suddath, William O
9 (RLIN) 139
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Torguson, Rebecca
9 (RLIN) 140
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Waksman, Ron
9 (RLIN) 30
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Xue, Zhenyi
9 (RLIN) 141
790 ## - Authors
All authors Ben-Dor I, Gaglia MA Jr, Hauville C, Kent KM, Laynez-Carnicero A, Lindsay J, Maluenda G, Pichard AD, Sardi GL, Satler LF, Suddath WO, Torguson R, Waksman R, Xue Z
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="http://dx.doi.org/10.1016/j.amjcard.2011.09.016">http://dx.doi.org/10.1016/j.amjcard.2011.09.016</a>
Public note http://dx.doi.org/10.1016/j.amjcard.2011.09.016
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Source of classification or shelving scheme Other/Generic Classification Scheme
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 09/17/2013   22112742 22112742 09/17/2013 09/17/2013 Journal Article

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