Safety and efficacy of MitraClip in acutely ill (NYHA Class IV) patients with mitral regurgitation: Results from the global EXPAND study. (Record no. 12836)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03839nam a22005657a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 230316s20232023 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 2055-5822 |
| 024 ## - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1002/ehf2.14273 [doi] |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| PMID | 36599332 |
| 245 ## - TITLE STATEMENT | |
| Title | Safety and efficacy of MitraClip in acutely ill (NYHA Class IV) patients with mitral regurgitation: Results from the global EXPAND study. |
| 247 ## - FORMER TITLE | |
| Title | Safety and efficacy of MitraClip in acutely ill (NYHA Class IV) patients with mitral regurgitation: Results from the global EXPAND study. |
| 251 ## - Source | |
| Source | ESC heart failure. 10(2):1122-1132, 2023 04. |
| 252 ## - Abbreviated Source | |
| Abbreviated source | ESC Heart Fail. 10(2):1122-1132, 2023 04. |
| 253 ## - Journal Name | |
| Journal name | ESC heart failure |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Manufacturer | FY2023 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Year | 2023 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Publication date | 2023 04 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] | |
| Publication status | ppublish |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] | |
| Medline status | MEDLINE |
| 266 ## - Date added to catalog | |
| Date updated in catalog | 2023-07-03 |
| 267 ## - Original year | |
| Original year | 2023 |
| 268 ## - Previous citation | |
| -- | ESC heart failure. 2023 Jan 04 |
| 269 ## - Original dates | |
| -- | ESC Heart Fail. 2023 Jan 04 |
| 269 ## - Original dates | |
| Original fiscal year | FY2023 |
| 269 ## - Original dates | |
| -- | 2023 Jan 04 |
| 269 ## - Original dates | |
| -- | aheadofprint |
| 269 ## - Original dates | |
| -- | Publisher |
| 520 ## - SUMMARY, ETC. | |
| Abstract | AIM: Patients with severe mitral regurgitation (MR) and acute heart failure (HF) have refractory symptoms without adequate response to medical therapy. The objective of this analysis was to assess the impact of the MitraClip device in acutely ill HF patients, characterized by NYHA Class IV at baseline, in a real-world, contemporary setting. |
| 520 ## - SUMMARY, ETC. | |
| Abstract | CONCLUSION: In the prospective, real-world EXPAND study, MitraClip in patients with severe MR and NYHA Class IV was found to be safe and effective in treating MR, and significantly improving QoL and long-term clinical outcomes. Copyright � 2023 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. |
| 520 ## - SUMMARY, ETC. | |
| Abstract | METHODS AND RESULTS: EXPAND was a prospective, multicenter, international study enrolling patients with MR who consented to receive the MitraClip System at 57 sites globally. The study outcomes included acute procedural success (APS), quality of life, heart failure hospitalizations (HFH), and all-cause mortality. The study population comprised 1,041 patients, with 118 patients having baseline NYHA Class IV, and 922 having baseline NYHA Class I/II/III. NYHA Class IV patients had a significantly higher rate of baseline co-morbidities and secondary MR aetiology compared with NYHA Class I/II/III patients. APS was achieved in 92.4% of NYHA Class IV patients and significant improvement in MR grade to <=Mild (1+) in 90.7% of subjects at 30 days and 92.9% at 1 year was observed. 1-year-mortality was higher in the NYHA Class IV subjects compared with the NYHA Class I/II/III subjects (29.2% vs. 17.7%, P < 0.01). Significant improvement in functional capacity assessed by NYHA Functional Class and Quality of Life assessed through KCCQ score was observed. At 1 year, 72.6% of NYHA Class IV subjects improved to NYHA Class I/II and DELTAKCCQ was 31.2 (24.1, 38.3) compared with baseline. |
| 546 ## - LANGUAGE NOTE | |
| Language note | English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | *Heart Failure |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | *Mitral Valve Insufficiency |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Heart Failure/co [Complications] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Heart Failure/su [Surgery] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mitral Valve Insufficiency/co [Complications] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mitral Valve Insufficiency/su [Surgery] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Prospective Studies |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Quality of Life |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Treatment Outcome |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Indexing | Automated |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME | |
| Institution | MedStar Health Research Institute |
| 657 ## - INDEX TERM--FUNCTION | |
| Medline publication type | Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Local Authors | Asch, Federico M |
| Institution Code | MHRI |
| 790 ## - Authors | |
| All authors | Shuvy M |
| -- | von Bardeleben RS |
| -- | Grasso C |
| -- | Raake P |
| -- | Lurz P |
| -- | Zamorano JL |
| -- | Asch F |
| -- | Kar S |
| -- | Maisano F |
| -- | EXPAND Investigators |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| DOI | <a href="https://dx.doi.org/10.1002/ehf2.14273">https://dx.doi.org/10.1002/ehf2.14273</a> |
| Public note | https://dx.doi.org/10.1002/ehf2.14273 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Item type description | Journal Article |
No items available.