Life Events, Caregiving, and Risk of Autoimmune Rheumatic Diseases in the Women's Health Initiative Observational Study. (Record no. 13056)
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fixed length control field | 03149nam a22003737a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 230815s20232023 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
International Standard Serial Number | 2151-464X |
024 ## - OTHER STANDARD IDENTIFIER | |
Standard number or code | 10.1002/acr.25164 [doi] |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
PMID | 37230960 |
245 ## - TITLE STATEMENT | |
Title | Life Events, Caregiving, and Risk of Autoimmune Rheumatic Diseases in the Women's Health Initiative Observational Study. |
251 ## - Source | |
Source | Arthritis care & research. 2023 May 25 |
252 ## - Abbreviated Source | |
Abbreviated source | Arthritis Care Res (Hoboken). 2023 May 25 |
253 ## - Journal Name | |
Journal name | Arthritis care & research |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Year | 2023 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Manufacturer | FY2023 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Publication date | 2023 May 25 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] | |
Publication status | aheadofprint |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] | |
Medline status | Publisher |
266 ## - Date added to catalog | |
Date added to catalog | 2023-08-15 |
520 ## - SUMMARY, ETC. | |
Abstract | CONCLUSION: Our findings support the idea that diverse stressors may increase risk of developing probable RA or SLE in postmenopausal women, supporting the need for further studies in autoimmune rheumatic diseases, including childhood adverse events, life event trajectories, and modifying psychosocial and socioeconomic factors. Copyright © 2023 American College of Rheumatology. This article has been contributed to by U.S. Government employees and their work is in the public domain in the USA. |
520 ## - SUMMARY, ETC. | |
Abstract | METHODS: The sample of postmenopausal women included 211 incident RA or SLE cases reported within 3 years after enrollment, confirmed by use of disease-modifying antirheumatic drugs (i.e., probable RA/SLE), and 76,648 noncases. Baseline questionnaires asked about life events in the past year, caregiving, and social support. We used Cox regression models to calculate hazard ratios (HR) and 95% confidence intervals (95% CIs), adjusting for age, race/ethnicity, occupational class, education, pack-years of smoking and BMI. |
520 ## - SUMMARY, ETC. | |
Abstract | OBJECTIVE: Growing evidence suggests psychosocial stressors may increase risk of developing autoimmune disease. We examined stressful life events and caregiving in relation to incident rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) in the Women's Health Initiative Observational Study cohort. |
520 ## - SUMMARY, ETC. | |
Abstract | RESULTS: Incident RA/SLE was associated with reporting 3 or more life events (e.g., age-adjusted HR 1.70 [95% CI 1.14, 2.53]; P for trend = 0.0026). Elevated HRs were noted for physical (HR 2.48 [95% CI 1.02, 6.04]) and verbal (HR 1.34 [0.89, 2.02]) abuse (P for trend = 0.0614), 2 or more interpersonal events (HR 1.23 [95% CI 0.87, 1.73]; P for trend = 0.2403), financial stress (HR 1.22 [95% CI 0.90, 1.64]), and caregiving 3 or more days per week (HR 1.25 [95% CI 0.87, 1.81]; P for trend = 0.2571). Results were similar, excluding women with baseline symptoms of depression or moderate-to-severe joint pain in the absence of diagnosed arthritis. |
546 ## - LANGUAGE NOTE | |
Language note | English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | IN PROCESS -- NOT YET INDEXED |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Indexing | Automated |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME | |
Institution | MedStar Health Research Institute |
657 ## - INDEX TERM--FUNCTION | |
Medline publication type | Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Local Authors | Howard, Barbara V |
Institution Code | MHRI |
790 ## - Authors | |
All authors | de Roos AJ, Howard BV, Parks CG, Pettinger M, Tindle HA, Walitt BT |
856 ## - ELECTRONIC LOCATION AND ACCESS | |
DOI | <a href="https://dx.doi.org/10.1002/acr.25164">https://dx.doi.org/10.1002/acr.25164</a> |
Public note | https://dx.doi.org/10.1002/acr.25164 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Koha item type | Journal Article |
Item type description | Article |
No items available.