Statistical Fragility of Randomized Controlled Trials Evaluating Rehabilitation After Arthroscopic Rotator Cuff Repair. [Review] (Record no. 13310)

MARC details
000 -LEADER
fixed length control field 03450nam a22004937a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 231004s20232023 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 2325-9671
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1177_23259671231184946 [pii]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1177/23259671231184946 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code PMC10392395 [pmc]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 37533502
245 ## - TITLE STATEMENT
Title Statistical Fragility of Randomized Controlled Trials Evaluating Rehabilitation After Arthroscopic Rotator Cuff Repair. [Review]
251 ## - Source
Source Orthopaedic Journal of Sports Medicine. 11(7):23259671231184946, 2023 Jul.
252 ## - Abbreviated Source
Abbreviated source Orthop. j. sports med.. 11(7):23259671231184946, 2023 Jul.
253 ## - Journal Name
Journal name Orthopaedic journal of sports medicine
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2023
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2024
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Publication date 2023 Jul
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status epublish
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Medline status PubMed-not-MEDLINE
266 ## - Date added to catalog
Date added to catalog 2023-10-04
520 ## - SUMMARY, ETC.
Abstract Background: Clinical decision-making often relies on evidence-based medicine, derived from objective data with conventional and rigorous statistical tests to evaluate significance. The literature surrounding rehabilitation after rotator cuff repair (RCR) is conflicting, with no defined standard of practice.
520 ## - SUMMARY, ETC.
Abstract Conclusion: The results of RCT studies of RCR rehabilitation protocols are moderately fragile, something clinicians should be aware of when implementing study results into practice. We recommend the inclusion of FI and FQ in addition to standard P values when reporting statistical results in future RCTs with dichotomous outcome variables on this topic. Copyright © The Author(s) 2023.
520 ## - SUMMARY, ETC.
Abstract Methods: A systematic review was performed according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines by searching the PubMed, Cochrane Library, and Embase databases for RCTs evaluating rehabilitation protocols after arthroscopic RCRs from 2000 to June 1, 2022. The FI was determined by manipulating the dichotomous outcome events from each article until a reversal of significance with 2 x 2 contingency tables was achieved. The FQ was determined by dividing the FI by the sample size.
520 ## - SUMMARY, ETC.
Abstract Purpose: To determine the fragility index (FI) and the fragility quotient (FQ) of randomized controlled trials (RCTs) evaluating rehabilitation protocols after RCR.
520 ## - SUMMARY, ETC.
Abstract Results: Fourteen RCTs with 48 dichotomous outcomes were ultimately included for analysis. The mean FI for the included dichotomous outcomes was 4 (interquartile range, 3-6), suggesting that the reversal of 4 events is required to change study significance. The mean FQ was 0.048. Of the RCTs that reported data regarding loss to follow-up, most studies (58.5%) indicated that >4 patients had been lost to follow-up.
520 ## - SUMMARY, ETC.
Abstract Study Design: Systematic review.
546 ## - LANGUAGE NOTE
Language note English
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Union Memorial Hospital
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Union Memorial Hospital
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Union Memorial Hospital
656 ## - INDEX TERM--OCCUPATION
Department Orthopaedic Surgery
656 ## - INDEX TERM--OCCUPATION
Department Orthopaedic Surgery Residency
656 ## - INDEX TERM--OCCUPATION
Department Orthopedics
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
657 ## - INDEX TERM--FUNCTION
Medline publication type Review
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Murthi, Anand M
Institution Code MUMH
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Wright, Melissa A
Institution Code MUMH
790 ## - Authors
All authors Murthi AM, Sequeira SB, Wright MA
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Sequeira, Sean
Institution Code MUMH
Program Orthopaedic Surgery Residency
Degree MD
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1177/23259671231184946">https://dx.doi.org/10.1177/23259671231184946</a>
Public note https://dx.doi.org/10.1177/23259671231184946
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 10/04/2023   37533502 37533502 10/04/2023 10/04/2023 Journal Article

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