Funding Bias in Shoulder Arthroplasty Research. [Review] (Record no. 14166)

MARC details
000 -LEADER
fixed length control field 03948nam a22004217a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 240723s20242024 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1058-2746
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code S1058-2746(24)00264-7 [pii]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 38642875
245 ## - TITLE STATEMENT
Title Funding Bias in Shoulder Arthroplasty Research. [Review]
251 ## - Source
Source Journal of Shoulder & Elbow Surgery. 2024 Apr 18
252 ## - Abbreviated Source
Abbreviated source J Shoulder Elbow Surg. 2024 Apr 18
253 ## - Journal Name
Journal name Journal of shoulder and elbow surgery
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2024
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Publication date 2024 Apr 18
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status aheadofprint
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Medline status Publisher
266 ## - Date added to catalog
Date added to catalog 2024-07-23
501 ## - WITH NOTE
Local holdings Available online from MWHC library: 1995 - present, Available in print through MWHC library:2004 - 2007
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: Prior research has shown that industry funding can impact the outcomes reported in medical literature. Limited data exists on the degree of bias that industry funding may have on shoulder arthroplasty literature outside of the Journal of Shoulder and Elbow Surgery. The purpose of this study is to characterize the type and frequency of funding for recently published shoulder arthroplasty studies and the impact of industry funding on reported outcomes. We hypothesized that studies with industry funding are more likely to report positive outcomes than those without.
520 ## - SUMMARY, ETC.
Abstract CONCLUSION: The results of this study suggest that there is a significant relationship between conflicts of interest and the primary outcome of shoulder arthroplasty studies, beyond the overall positive publication bias. Studies with industry funding and author conflicts of interest both report positive outcomes more frequently than negative outcomes. Shoulder surgeons should be aware of this potential bias when choosing to base clinical practice on published data. Copyright © 2024. Published by Elsevier Inc.
520 ## - SUMMARY, ETC.
Abstract MATERIALS/METHOD: We performed a retrospective study searching all articles with the term "shoulder arthroplasty," "reverse shoulder arthroplasty," "anatomic total shoulder arthroplasty," or "total shoulder arthroplasty" on PubMed from the years January 2020 to December 2022. The primary outcome of studies was coded as either positive, negative, or neutral. A positive result was defined as one in which the null hypothesis was rejected. A negative result was defined as one in which the result did not favor the group in which the industry-funded implant was used. A neutral result was defined as one in which the null hypothesis was confirmed. Article funding type, subcategorized as National Institute of Health (NIH) funding or industry funding was recorded. Author disclosures were recorded to determine conflicts of interest. Statistical analysis was conducted using the Chi-squared test and Fisher exact test.
520 ## - SUMMARY, ETC.
Abstract RESULTS: 750 articles reported on either conflict of interest or funding source and were included in the study. Of the total number of industry funded studies the majority were found to have a positive primary endpoint (58.1%, 104/179), as compared to a negative (7.8%, 14/179), or neutral endpoint (33.5%, 60/179) (p=0.004). 363 articles reported an author conflicts of interest and the majority of these studies had positive primary endpoint (55.6%, 202/363) as compared to negative (9.1%, 33/363) or neutral endpoints (34.4%, 125/363)(p=.002).
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Indexing Automated
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Union Memorial Hospital
656 ## - INDEX TERM--OCCUPATION
Department Orthopaedic Surgery Residency
656 ## - INDEX TERM--OCCUPATION
Department Orthopedics
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
657 ## - INDEX TERM--FUNCTION
Medline publication type Review
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Haislup, Brett
Institution Code MUMH
Program Orthopaedic Surgery Residency
Degree MD
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Murthi, Anand M
Institution Code MUMH
790 ## - Authors
All authors Haislup BD, Gupta S, Fleisher I, Murthi AM, Wright MA
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1016/j.jse.2024.03.016">https://dx.doi.org/10.1016/j.jse.2024.03.016</a>
Public note https://dx.doi.org/10.1016/j.jse.2024.03.016
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
              07/23/2024   38642875 38642875 07/23/2024 07/23/2024 Journal Article

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