Delayed Facial Nerve Dysfunction Following CyberKnife R Radiosurgery for Vestibular Schwannoma. (Record no. 14364)

MARC details
000 -LEADER
fixed length control field 03324nam a22004337a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 240807s20242024 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0023-852X
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 38963255
245 ## - TITLE STATEMENT
Title Delayed Facial Nerve Dysfunction Following CyberKnife R Radiosurgery for Vestibular Schwannoma.
251 ## - Source
Source Laryngoscope. 2024 Jul 04
252 ## - Abbreviated Source
Abbreviated source Laryngoscope. 2024 Jul 04
253 ## - Journal Name
Journal name The Laryngoscope
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2024
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2025
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Publication date 2024 Jul 04
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status aheadofprint
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Medline status Publisher
266 ## - Date added to catalog
Date added to catalog 2024-08-07
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Date Medline record created 2024/07/04 08:33
501 ## - WITH NOTE
Local holdings Available online from MWHC library: 1997 - present, Available in print through MWHC library: 1996 - 2003
520 ## - SUMMARY, ETC.
Abstract CONCLUSIONS: FND may represent an underrecognized sequelae of CyberKnife R radiosurgery for VS that can occur many months following treatment. Further studies are needed to elucidate the effect of differential radiation exposure to the facial nerve with FND following treatment.
520 ## - SUMMARY, ETC.
Abstract LEVEL OF EVIDENCE: III (Retrospective Cohort Study) Laryngoscope, 2024. Copyright © 2024 The American Laryngological, Rhinological and Otological Society, Inc.
520 ## - SUMMARY, ETC.
Abstract METHODS: Patients were identified who underwent CyberKnife R radiosurgery for VS at a single institution. Basic demographics, tumor characteristics, and facial nerve function were collected. Total radiation doses to tumor, internal auditory canal (IAC), and labyrinthine segment of facial nerve (LSFN) were evaluated.
520 ## - SUMMARY, ETC.
Abstract OBJECTIVE: The incidence and risk factors for facial nerve dysfunction (FND) following CyberKnife R therapy for vestibular schwannoma (VS) remain poorly understood. This study investigates whether differential radiation doses to vulnerable segments of the facial nerve may be associated with FND outcomes.
520 ## - SUMMARY, ETC.
Abstract RESULTS: Six out of 64 patients experienced FND following CyberKnife R treatment for VS (9.38%, 6/64). Patients with FND were compared to those without FND (control). Of the 64 patients, complete radiation records were obtained for 30 patients (6 FND vs. 24 control). There were no significant differences in demographic or tumor characteristics between control and FND cohorts. More severe FND (HB >= 4) had significantly larger tumors (3.74 vs. 1.27 cm3, p = 0.037) with directionally decreased time to FND (3.50 vs. 33.5 months, p = 0.106) than patients with HB < 4, respectively. There were directionally, nonsignificant differences between maximum radiation doses to the LSFN (2492.4 vs. 2557.0 cGy, p = 0.121) and IAC (2877.3 vs. 2895.5 cGy, p = 0.824) between the control and FND cohorts, respectively.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Indexing Automated
656 ## - INDEX TERM--OCCUPATION
Department MedStar Georgetown University Hospital/MedStar Washington Hospital Center
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Department Otolaryngology Residency
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Department Radiation Oncology Residency
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Chisolm, Paul
Institution Code MGUH
Program Otolaryngology Residency
Degree MD
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Conroy, Dylan
Institution Code MGUH
Program Radiation Oncology Residency
Degree MD
790 ## - Authors
All authors Johns JD, Ahn PH, Rashid AX, Conroy DR, Chisolm PF, Kim HJ
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1002/lary.31627">https://dx.doi.org/10.1002/lary.31627</a>
Public note https://dx.doi.org/10.1002/lary.31627
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Barcode Date last seen Price effective from Koha item type
              08/07/2024   38963255 08/07/2024 08/07/2024 Journal Article

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