Evaluation of pediatric patients for intestinal transplantation in the modern era. (Record no. 14407)

MARC details
000 -LEADER
fixed length control field 03328nam a22003857a 4500
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fixed length control field 240807s20242024 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0277-2116
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 38828781
245 ## - TITLE STATEMENT
Title Evaluation of pediatric patients for intestinal transplantation in the modern era.
251 ## - Source
Source Journal of Pediatric Gastroenterology & Nutrition. 2024 Jun 03
252 ## - Abbreviated Source
Abbreviated source J Pediatr Gastroenterol Nutr. 2024 Jun 03
253 ## - Journal Name
Journal name Journal of pediatric gastroenterology and nutrition
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2024
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Manufacturer FY2024
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Publication date 2024 Jun 03
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status aheadofprint
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Medline status Publisher
266 ## - Date added to catalog
Date added to catalog 2024-08-07
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Date Medline record created 2024/06/03 06:33
520 ## - SUMMARY, ETC.
Abstract CONCLUSIONS: Despite recent improvements in IF management, IFALD remains a prominent reason for ITx referral. Complications of IF inherent to ITx candidacy influence postevaluation and post-ITx survival. Copyright © 2024 European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.
520 ## - SUMMARY, ETC.
Abstract METHODS: Retrospective chart review of 97 patients evaluated for ITx from January 2014 to December 2021 including data from referring institutions and protocol laboratory testing, body imaging, endoscopy, and liver biopsy in selected cases. Survival analysis used Kaplan-Meier estimates and Cox proportional hazards regression.
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Abstract OBJECTIVES: To review recent evaluations of pediatric patients with intestinal failure (IF) for intestinal transplantation (ITx), waiting list decisions, and outcomes of patients listed and not listed for ITx at our center.
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Abstract RESULTS: Patients were referred almost entirely from outside institutions, one-third because of intestinal failure-associated liver disease (IFALD), two-thirds because of repeated infective and non-IFALD complications under minimally successful intestinal rehabilitation, and a single patient because of lost central vein access. The majority had short bowel syndrome (SBS). Waiting list placement was offered to 67 (69%) patients, 40 of whom for IFALD. The IFALD group was generally younger and more likely to have SBS, have received more parenteral nutrition, have demonstrated more evidence of chronic inflammation and have inferior kidney function compared to those offered ITx for non-IFALD complications and those not listed. ITx was performed in 53 patients. Superior postevaluation survival was independently associated with higher serum creatinine (hazard ratio [HR] 15.410, p = 014), whereas inferior postevaluation survival was associated with ITx (HR 0.515, p = 0.035) and higher serum fibrinogen (HR 0.994, p = 0.005).
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
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Indexing Automated
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Department MedStar Georgetown University Hospital/MedStar Washington Hospital Center
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Department Pediatrics Residency
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Medline publication type Journal Article
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Local Authors Ozler, Oguz
Institution Code MGUH
Program Pediatrics Residency
Degree MD
790 ## - Authors
All authors Bryan NS, Russell SC, Ozler O, Sugiguchi F, Yazigi NA, Khan KM, Ekong UD, Vitola BE, Guerra JF, Kroemer A, Fishbein TM, Matsumoto CS, Ghobrial SS, Kaufman SS
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1002/jpn3.12274">https://dx.doi.org/10.1002/jpn3.12274</a>
Public note https://dx.doi.org/10.1002/jpn3.12274
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Barcode Date last seen Price effective from Koha item type
              08/07/2024   38828781 08/07/2024 08/07/2024 Journal Article

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