MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03362nam a22004457a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
240807s20242024 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
|---|
| International Standard Serial Number |
2000-9666 |
| 024 ## - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
jchim-14-03-072 [pii] |
| 024 ## - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
PMC11259480 [pmc] |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| PMID |
39036577 |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
Endocrine Shades of Silicone Fillers: A Case of Calcitriol-mediated Hypercalcemia. |
| 251 ## - Source |
|---|
| Source |
Journal of Community Hospital Internal Medicine Perspectives. 14(3):72-76, 2024. |
| 252 ## - Abbreviated Source |
|---|
| Abbreviated source |
J Community Hosp Intern Med Perspect. 14(3):72-76, 2024. |
| 253 ## - Journal Name |
|---|
| Journal name |
Journal of community hospital internal medicine perspectives |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Year |
2024 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Manufacturer |
FY2025 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Publication date |
2024/07/22 05:35 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
|---|
| Publication status |
epublish |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
|---|
| Medline status |
PubMed-not-MEDLINE |
| 266 ## - Date added to catalog |
|---|
| Date added to catalog |
2024-08-07 |
| 520 ## - SUMMARY, ETC. |
|---|
| Abstract |
Background: The inflammatory reaction of foreign body granulomas (FBG) may be so vast that it leads to severe systemic effects. |
| 520 ## - SUMMARY, ETC. |
|---|
| Abstract |
Case report: A 42-year-old woman was referred to the ED with severe recurrent symptomatic hypercalcemia associated with worsening kidney function. She had presented multiple times with similar complaints. Severe hypercalcemia (13.8 mg/dL) was noted, with appropriately low PTH, elevated PTHrP, low 25-hydroxyvitamin D, and normal 1,25-dihydroxyvitamin D levels. She admitted having significant subcutaneous silicone filler injections in the hips six years prior. Admission workup revealed a normal 25-hydroxyvitamin D, but a marked elevation of 1,25-dihydroxyvitamin D (138 pg/mL). Whole-body PET-CT demonstrated moderate 2-18F-fluoro-2-deoxy-d-glucose (FDG) uptake within the subcutaneous adipose tissue of the lateral aspects of the gluteal regions. She was diagnosed with silicone filler injection-induced hypercalcemia, secondary to granulomatous inflammation. Her calcium level normalized a month after the initiation of prednisone. |
| 520 ## - SUMMARY, ETC. |
|---|
| Abstract |
Conclusion: Granulomatous inflammation from silicone filler injection can cause hypercalcemia by uncontrolled production of calcitriol and increased PTHrP production by macrophages and giant cells. Copyright © 2024 Greater Baltimore Medical Center. |
| 520 ## - SUMMARY, ETC. |
|---|
| Abstract |
Discussion: FBG may occur years after filler injection. In rare cases, a significant granulomatous immune response leads to uncontrolled production of calcitriol. Pro-inflammatory cytokines can also upregulate PTHrP expression in macrophages, further contributing to hypercalcemia. Treatment focuses on general hypercalcemia management and FBG remission, most effectively achieved with anti-inflammatory corticosteroid doses. Nevertheless, further studies are needed to evaluate its long-term treatment efficacy. |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Indexing |
Automated |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
|---|
| Institution |
MedStar Union Memorial Hospital |
| 656 ## - INDEX TERM--OCCUPATION |
|---|
| Department |
Hospitalist |
| 656 ## - INDEX TERM--OCCUPATION |
|---|
| Department |
Internal Medicine Residency |
| 657 ## - INDEX TERM--FUNCTION |
|---|
| Medline publication type |
Case Reports |
| 657 ## - INDEX TERM--FUNCTION |
|---|
| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Local Authors |
Antoni, Fidini |
| Institution Code |
MUMH |
| Program |
Internal Medicine Residency |
| Degree |
MD |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Local Authors |
Haas, Christopher |
| Institution Code |
MUMH |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Local Authors |
Madsen-Barbosa, Thayse L |
| Institution Code |
MUMH |
| Program |
Internal Medicine Residency |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Local Authors |
Martinez-Cruz, Maria |
| Institution Code |
MUMH |
| Program |
Internal Medicine Residency |
| 790 ## - Authors |
|---|
| All authors |
Martinez-Cruz M, Madsen-Barbosa TL, Antoni F, Haas C |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| DOI |
<a href="https://dx.doi.org/10.55729/2000-9666.1349">https://dx.doi.org/10.55729/2000-9666.1349</a> |
| Public note |
https://dx.doi.org/10.55729/2000-9666.1349 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Journal Article |
| Item type description |
Article |
