Spinal extramedullary hematopoiesis mimicking an epidural tumor in a patient with high-risk polycythemia vera: illustrative case. (Record no. 14459)

MARC details
000 -LEADER
fixed length control field 02687nam a22003977a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 240807s20242024 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 2694-1902
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code CASE23659 [pii]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 38976913
245 ## - TITLE STATEMENT
Title Spinal extramedullary hematopoiesis mimicking an epidural tumor in a patient with high-risk polycythemia vera: illustrative case.
251 ## - Source
Source Journal of Neurosurgery Case Lessons. 8(2), 2024 Jul 08.
252 ## - Abbreviated Source
Abbreviated source J. neurosurg., Case lessons. 8(2), 2024 Jul 08.
253 ## - Journal Name
Journal name Journal of neurosurgery. Case lessons
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2024
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2025
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Publication date 2024 Jul 08
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status epublish
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Medline status PubMed-not-MEDLINE
266 ## - Date added to catalog
Date added to catalog 2024-08-07
266 ## - Date added to catalog
Date Medline record created 2024/07/08 17:52
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: Here the authors present the case of a 43-year-old male with a history of T-cell lymphoma, which was treated with azacitidine plus cyclophosphamide, doxorubicin, vincristine, and prednisone and autologous hematopoietic cell transplant, and high-risk polycythemia vera (PCV) presenting with severe lower-back pain radiating to the bilateral legs with associated lower-extremity weakness and splenomegaly.
520 ## - SUMMARY, ETC.
Abstract LESSONS: EMH associated with PCV or myeloproliferative conditions occurring within the spine is a rare phenomenon without a standard treatment approach. https://thejns.org/doi/10.3171/CASE23659.
520 ## - SUMMARY, ETC.
Abstract OBSERVATIONS: T2-weighted magnetic resonance imaging revealed multilevel epidural lesions involving T1-10 and S1-2. Because of severe spinal canal stenosis, the patient underwent surgical decompression of T5-7, with immediate postoperative alleviation of the lower-extremity pain and complete resolution of the lower-leg weakness. Biopsy results revealed extramedullary hematopoiesis (EMH) mimicking a spinal epidural tumor. EMH is radiosensitive and displays a rapid response to low dosages, so the patient was further treated with palliative radiation therapy for residual tumors and symptom alleviation, as well as hydroxyurea and corticosteroids as indicated for cytoreduction.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Indexing Automated
656 ## - INDEX TERM--OCCUPATION
Department MedStar Georgetown University Hospital/MedStar Washington Hospital Center
656 ## - INDEX TERM--OCCUPATION
Department Neurosurgery Residency
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Department Radiation Oncology Residency
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Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Bhatnagar, Akrita
Institution Code MGUH
Program Radiation Oncology Residency
Degree MD
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Breton, Jeffrey
Institution Code MGUH
Program Neurosurgery Residency
Degree MD
790 ## - Authors
All authors Hawkins AN, Breton JM, Bhatnagar A, Paudel N, Voyadzis JM
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.3171/CASE23659">https://dx.doi.org/10.3171/CASE23659</a>
Public note https://dx.doi.org/10.3171/CASE23659
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
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              08/07/2024   38976913 08/07/2024 08/07/2024 Journal Article

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