Gene expression profiles of fatigued fibromyalgia patients with different categories of pain and catastrophizing: a preliminary report. (Record no. 1496)

MARC details
000 -LEADER
fixed length control field 03078nam a22005057a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 140821s20132013 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0029-6554
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 23684314
245 ## - TITLE STATEMENT
Title Gene expression profiles of fatigued fibromyalgia patients with different categories of pain and catastrophizing: a preliminary report.
251 ## - Source
Source Nursing Outlook. 61(4):216-224.e2, 2013 Jul-Aug.
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Abbreviated source Nurs Outlook. 61(4):216-224.e2, 2013 Jul-Aug.
253 ## - Journal Name
Journal name Nursing outlook
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2013
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Manufacturer FY2014
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Date added to catalog 2014-08-21
501 ## - WITH NOTE
Local holdings Available online from MWHC library: 1995 - present, Available in print through MWHC library:1999-2007
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: Fibromyalgia (FM) is a chronic condition characterized by diffused musculoskeletal pain and overwhelming fatigue.
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Abstract CONCLUSION: Findings provide preliminary evidence that specific physiological pathways may possibly delineate pain and catastrophizing mechanisms. Further investigation via the use of a larger and more homogenous sample is warranted. Published by Mosby, Inc.
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Abstract DISCUSSION: Differential expression of 107 genes between the high and low pain groups and 139 genes between the high and low catastrophizing groups (over 2.0-fold 20140821, p < .05) were observed. Network analyses showed interferon signaling and interferon regulatory activation factor pathways distinguished between the pain groups whereas dendritic cell maturation delineated between the catastrophizing groups.
520 ## - SUMMARY, ETC.
Abstract METHODS: Nine women with FM enrolled in an active Medstar Research Institute protocol were included in the gene expression analyses of peripheral blood RNA via Affymetrix GeneChip Human Genome U133 Plus 2.0 array (Santa Clara, CA). Scores from Brief Pain Inventory, Pain Catastrophizing Scale, and Multidimensional Fatigue Inventory categorized the nine participants into pain (high, n = 3; low, n = 6) and catastrophizing groups (high, n = 5; low, n = 4).
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Abstract PURPOSE: To compare the gene expression profiles of fatigued FM women with different levels of pain and catastrophizing.
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Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Catastrophization/ge [Genetics]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Fatigue/ge [Genetics]
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Topical term or geographic name entry element *Fibromyalgia/ge [Genetics]
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Topical term or geographic name entry element *Pain/ge [Genetics]
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Topical term or geographic name entry element Adult
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Topical term or geographic name entry element Female
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Topical term or geographic name entry element Gene Expression Profiling
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Topical term or geographic name entry element Genome-Wide Association Study
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Topical term or geographic name entry element Humans
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Topical term or geographic name entry element Middle Aged
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Topical term or geographic name entry element Oligonucleotide Array Sequence Analysis
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Institution MedStar Washington Hospital Center
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Department Medicine/Rheumatology
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Medline publication type Comparative Study
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Medline publication type Journal Article
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Medline publication type Research Support, N.I.H., Intramural
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Medline publication type Research Support, Non-U.S. Gov't
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Walitt, Brian
790 ## - Authors
All authors Lukkahatai N, Majors B, Reddy S, Saligan LN, Walitt B
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="http://dx.doi.org/10.1016/j.outlook.2013.03.007">http://dx.doi.org/10.1016/j.outlook.2013.03.007</a>
Public note http://dx.doi.org/10.1016/j.outlook.2013.03.007
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 08/21/2014   23684314 23684314 08/21/2014 08/21/2014 Journal Article

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