Long-term outcomes after cytoreductive surgery and HIPEC for morcellated uterine leiomyosarcoma; A case series. (Record no. 18)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03155nam a22003857a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 221213s20212021 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 2352-5789 |
| 024 ## - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1016/j.gore.2021.100741 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER | |
| Standard number or code | PMC7970133 [pmc] |
| 024 ## - OTHER STANDARD IDENTIFIER | |
| Standard number or code | S2352-5789(21)00046-1 [pii] |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| PMID | 33748383 |
| 245 ## - TITLE STATEMENT | |
| Title | Long-term outcomes after cytoreductive surgery and HIPEC for morcellated uterine leiomyosarcoma; A case series. |
| 251 ## - Source | |
| Source | Gynecologic Oncology Reports. 36:100741, 2021 May. |
| 252 ## - Abbreviated Source | |
| Abbreviated source | Gynecol Oncol Rep. 36:100741, 2021 May. |
| 253 ## - Journal Name | |
| Journal name | Gynecologic oncology reports |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Year | 2021 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Manufacturer | FY2021 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Publication date | 2021 May |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] | |
| Publication status | epublish |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] | |
| Medline status | PubMed-not-MEDLINE |
| 266 ## - Date added to catalog | |
| Date added to catalog | 2022-12-13 |
| 520 ## - SUMMARY, ETC. | |
| Abstract | Uterine leiomyosarcoma (uLMS) is a rare aggressive malignant mesenchymal tumor with high risk of recurrence and poor prognosis regardless of stage. It is often diagnosed postoperatively following myomectomy, hysterectomy or supracervical hysterectomy for presumed benign disease. Primary surgery at the diagnosis of uLMS is considered to affect outcomes. If the tumor was morcellated, the oncologist will encounter special problems that require knowledgeable management of peritoneal metastases. We previously reported that six patients who successfully underwent cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) plus early postoperative intraperitoneal chemotherapy (EPIC) to manage the disease dissemination that must occur following morcellation. This is a study for long-term outcome of these patients. Six patients were treated with an absence of grade IV adverse events and no mortality. The median Peritoneal Cancer Index (PCI) was 18 and complete cytoreduction without peritoneal metastases visualized within the operative field at the completion of the surgical procedure (CC-0) was achieved in all patients. One patient was diagnosed leiomyomatosis peritonealis postoperatively. Among five patients who were confirmed uterine leiomyosarcoma, the 3-year overall survival was 40.0% and 5-year overall survival was 20.0% with the median follow-up of 18 months (range 5-73 months). The patient with PCI 0 at the time of CRS showed no evidence of disease (NED) at 73 months. We believe that prophylactic CRS contributed her favorable outcome. Therapeutic options for patients with uLMS post-morcellation are limited. Currently, CRS and HIPEC plus EPIC followed by adjuvant systemic chemotherapy may be considered an option for treatment. Further studies in a larger number of patients are needed. Copyright © 2021 The Authors. Published by Elsevier Inc. |
| 546 ## - LANGUAGE NOTE | |
| Language note | English |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME | |
| Institution | MedStar Washington Hospital Center |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME | |
| Institution | Washington Cancer Institute |
| 656 ## - INDEX TERM--OCCUPATION | |
| Department | Obstetrics and Gynecology |
| 657 ## - INDEX TERM--FUNCTION | |
| Medline publication type | Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Local Authors | Dainty, Louis A |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Local Authors | Sugarbaker, Paul H |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Local Authors | Yasukawa, Maya |
| 790 ## - Authors | |
| All authors | Dainty LA, Sugarbaker PH, Yasukawa M |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| DOI | <a href="https://dx.doi.org/10.1016/j.gore.2021.100741">https://dx.doi.org/10.1016/j.gore.2021.100741</a> |
| Public note | https://dx.doi.org/10.1016/j.gore.2021.100741 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Item type description | Article |
| Withdrawn status | Lost status | Damaged status | Not for loan | Collection | Home library | Current library | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MedStar Authors Catalog | MedStar Authors Catalog | 12/13/2022 | 33748383 | 33748383 | 12/13/2022 | 12/13/2022 | Journal Article |