MARC details
| 000 -LEADER |
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| fixed length control field |
02852nam a22003497a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
170526s20132013 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
0094-2405 |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
28518570 |
| 245 ## - TITLE STATEMENT |
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| Title |
SU-E-T-327: Dosimetry and Implementation of High-Dose Rate MLC-Based GRID Therapy Using a 6MV Flattened Filter Free (FFF) Photon Beam. |
| 251 ## - Source |
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| Source |
Medical Physics. 40(6Part15):279, 2013 Jun |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
Med Phys. 40(6Part15):279, 2013 Jun |
| 253 ## - Journal Name |
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| Journal name |
Medical physics |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2013 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2013 |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2017-05-26 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSION: 6MV FFF MLC-based GRID therapy aligned accurately with IGRT showed advantages in the higher dose delivery by more than 2 times reducing treatment time over a conventional delivery. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Copyright © 2013 American Association of Physicists in Medicine. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
METHODS: Planning for MLC GRID therapy was done by a Varian Eclipse treatment planning system. The dose plane at depth of 5cm was exported for a dose comparison between the calculated and measured data. MLC GRID with the projected square openings of 10 x 10 mm at the isocenter was studied using 6MV FFF photons at a dose rate of 1400MU/min. Four separate MLC-shaped beams of each with two columns of GRID openings were automated for delivery by a Varian TrueBeam linear accelerator. MLC GRID was characterized with depth dose, profile and output using an IBA scanning system. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
PURPOSE: To dosimetrically characterize high-dose rate multileaf collimator (MLC)-based, spatially-fractionated GRID therapy (MLC GRID) using a 6MV flattened filter free (FFF) photon beam delivered from a Varian TrueBeam linear accelerator. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
RESULTS: 6MV FFF GRID patterns recorded using films and EPID were found to be consistent in both aperture sizes and alignment. A MapCheck was used to validate the 16-20 cm field of a 6MV FFF GRID with a pass rate of 97% at 3%/3mm criteria. The ratio of the openings to the blocked area was quantified to be 25% with a valley-to-peak ratio of about 16.5% from the beam profiles in the central aperture. GRID therapy is a technique to treat advanced bulky tumor in a single or a few fractions by delivering a dose of 12 to 20Gy to tumors that do not respond to conventional fractionation schemes. Four abutting GRID fields with 3000 MU to each field took only about 9 minutes using a 6MV FFF beam, but took more than 30 minutes for delivery at 400 MU/min. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
RadAmerica, LLC-MedStar Health |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Dou, K |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Lerma, F |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Li, B |
| 790 ## - Authors |
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| All authors |
Dou K, Jacobs M, Lerma F, Li B |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1118/1.4814761">https://dx.doi.org/10.1118/1.4814761</a> |
| Public note |
https://dx.doi.org/10.1118/1.4814761 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
