MARC details
| 000 -LEADER |
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| fixed length control field |
03956nam a22004577a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
170829s20172017 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
1934-1482 |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
28827206 |
| 245 ## - TITLE STATEMENT |
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| Title |
Relationship Between Gonadal Function and Cardiometabolic Risk in Young Men with Chronic Spinal Cord Injury. |
| 251 ## - Source |
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| Source |
Pm & R. , 2017 Aug 18 |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
PM R. , 2017 Aug 18 |
| 252 ## - Abbreviated Source |
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| Former abbreviated source |
Replace date, check 856 |
| 253 ## - Journal Name |
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| Journal name |
PM & R : the journal of injury, function, and rehabilitation |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2017 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2018 |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2017-08-29 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
BACKGROUND: We previously reported that young men with chronic spinal cord injury (SCI) have a higher prevalence of testosterone deficiency when compared to an age-matched healthy control population. Young men with SCI are also at increased risk for developing cardiometabolic dysfunction after injury. It is unclear whether or not testosterone deficiency is associated with heightened cardiometabolic risk in men with SCI. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSIONS: In young men with chronic SCI, who undergo an accelerated aging process post-injury, hypogonadism is associated with an unfavorable cardiometabolic risk profile. Further research is needed to determine if a causal relationship exists between hypogonadism and heightened cardiometabolic risk in men with SCI, and whether routine screening for testosterone deficiency is warranted in this population. Copyright (c) 2017 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
DESIGN: Secondary cross-sectional analysis. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
MAIN OUTCOME MEASUREMENTS: Surrogate markers of cardiometabolic risk among men based on the level of total testosterone (TT)(<=300, 301-500, or >500 ng/dL) and free testosterone (fT) (<=9 or >9 ng/dL). Comparisons were made between men with normal and low TT or fT. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
METHODS: Plasma concentrations of testosterone, lipids, inflammatory markers (CRP and IL-6), HbA1C%, glucose, and insulin were measured in a fasting state using standard assays. A two-hour oral glucose tolerance test (OGTT) and Framingham Risk Score (FRS) were assessed for each subject. Body composition was assessed by DXA scan. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
OBJECTIVE: To investigate associations among levels of testosterone in young men with chronic SCI and surrogate markers of cardiometabolic risk. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
PARTICIPANTS: Men (n=58) aged 18-45 with chronic (>=1 year), motor complete SCI without co-morbidities or use of testosterone therapy. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
RESULTS: FRS was significantly higher in men with low fT (P<.05). Percent body fat (P<.05) and waist-to-hip ratio (P<.05), but not body mass index (BMI) (P>.08), were higher in men with low TT or low fT. Men with low TT or low fT had lower high density lipoprotein cholesterol (HDL) levels (P<.05) without differences in fasting triglycerides (P>.1) or low density lipoprotein cholesterol (LDL) (P>.07). Men with low TT had higher levels of inflammatory markers CRP (P<.05) and IL-6 (P<.05). Men with low TT or low fT had higher fasting glucose (P<.05) and greater insulin resistance (P<.04), without differences in HbA1C% (P>.8). |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
SETTING: Rehabilitation research centers in Washington, DC, and Miami, Florida, USA. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar National Rehabilitation Network |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Washington Hospital Center |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Medicine/Endocrinology |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Physical Medicine and Rehabilitation |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Groah, Suzanne L |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Sullivan, Shannon D |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Tefera, Eshetu |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Tinsley, Emily |
| 790 ## - Authors |
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| All authors |
Groah S, Nash MS, Sullivan SD, Tefara E, Tinsley E |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1016/j.pmrj.2017.08.404">https://dx.doi.org/10.1016/j.pmrj.2017.08.404</a> |
| Public note |
https://dx.doi.org/10.1016/j.pmrj.2017.08.404 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
