MARC details
| 000 -LEADER |
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| fixed length control field |
02444nam a22003977a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
221018s20222022 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
2214-2509 |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1016/j.idcr.2022.e01616 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
PMC9472058 [pmc] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
S2214-2509(22)00244-X [pii] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
36119758 |
| 245 ## - TITLE STATEMENT |
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| Title |
A mild, self-resolving case of Epstein-Barr virus-induced hemophagocytic lymphohistiocytosis. |
| 251 ## - Source |
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| Source |
IDCases. 30:e01616, 2022. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
IDCases. 30:e01616, 2022. |
| 253 ## - Journal Name |
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| Journal name |
IDCases |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2022 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2023 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
epublish |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Medline status |
PubMed-not-MEDLINE |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2022-10-20 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Hemophagocytic lymphohistiocytosis (HLH) is a multisystem disease caused by an excessive activation of the immune system. In most instances, HLH can be fatal without treatment; a life-threatening syndrome driven by a dysregulated immune system and activation of macrophages resulting in cytokine release and consequent cellular damage. HLH can occur as a consequence of multiple genetic abnormalities or environmental triggers. We present an interesting case of mild, self-resolving, HLH due to Epstein-Barr Virus (EBV) infection in a young woman. The best-known diagnostic criteria are based on the HLH-2004 trial, incorporating either the presence of known mutations or five of eight clinical and laboratory findings. Prompt initiation of etoposide-containing therapy is associated with improved survival. Rituximab, an anti-CD20 antibody, can also remove EBV-harboring B-cells and improve outcomes. In a rare subset of patients, the disease can spontaneously resolve without any therapeutic interventions thus sparing the patients from toxic therapies. Copyright © 2022 The Authors. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Franklin Square Medical Center |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Union Memorial Hospital |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Hospitalist |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Internal Medicine Residency |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Case Reports |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Adhikari, Biplov |
| Institution Code |
MUMH |
| Program |
Internal Medicine Residency |
| Degree |
MBBS |
| Resident year |
Resident PGY 2 |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Haas, Christopher |
| Institution Code |
MUMH |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Local Authors |
Rao, Shiavax |
| Institution Code |
MUMH |
| Program |
Internal Medicine Residency |
| Degree |
MD |
| Resident year |
Resident PGY 3 |
| 790 ## - Authors |
|---|
| All authors |
Adhikari B, Haas CJ, Rao SJ |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1016/j.idcr.2022.e01616">https://dx.doi.org/10.1016/j.idcr.2022.e01616</a> |
| Public note |
https://dx.doi.org/10.1016/j.idcr.2022.e01616 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Journal Article |
| Item type description |
Article |
