MARC details
| 000 -LEADER |
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| fixed length control field |
03220nam a22003617a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
180315s20182018 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
1538-7836 |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1111/jth.13993 [doi] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
29504242 |
| 245 ## - TITLE STATEMENT |
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| Title |
Vasomotor symptoms and the risk of incident venous thrombosis in postmenopausal women. |
| 251 ## - Source |
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| Source |
Journal of Thrombosis & Haemostasis. 2018 Mar 05 |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
J Thromb Haemost. 2018 Mar 05 |
| 253 ## - Journal Name |
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| Journal name |
Journal of thrombosis and haemostasis : JTH |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2018 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2018 |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2018-04-20 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
BACKGROUND: Vasomotor symptoms may be markers of changes in cardiovascular risk, but it is unknown whether these symptoms are associated with the risk of venous thrombosis (VT). |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSIONS: Although vasomotor symptoms have been associated with the risk of other cardiovascular events in published studies, our findings do not suggest that vasomotor symptoms are a marker of VT risk. This article is protected by copyright. All rights reserved. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Copyright This article is protected by copyright. All rights reserved. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
METHODS: This cohort study included participants of the Women's Health Initiative (WHI) Hormone Therapy Trials (n=24,508) and Observational Study (n=87,783), analyzed separately. At baseline, women reported whether hot flashes or night sweats were present and if so, their severity. Using Cox proportional hazards models, we estimated VT risk associated with vasomotor symptom presence and severity, adjusted for potential explanatory variables: age, BMI, smoking status, race/ethnicity, and time-varying current hormone therapy use. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
OBJECTIVE: To evaluate the association of vasomotor symptom presence and severity with incident VT risk among postmenopausal women, independent of potential explanatory variables. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
RESULTS: At baseline, WHI Hormone Therapy Trial participants were 64 years of age and WHI Observational Study participants were 63 years of age, on average. In the WHI Hormone Therapy Trials over a median of 8.2 years of follow-up, 522 women experienced a VT event. In the WHI Observational Study, over 7.9 years of follow-up, 1,103 women experienced a VT event. In adjusted analyses, we found no evidence of an association between vasomotor symptom presence (HR<sub>adj</sub> =0.91 [95%CI: 0.75, 1.1] in WHI Hormone Therapy Trials; HR<sub>adj</sub> =1.1 [95%CI: 0.99, 1.3] in WHI Observational Study) or severity (HR<sub>adj</sub> for severe vs. mild=0.99 [95%CI: 0.53, 1.9] in WHI Hormone Therapy Trials; HR<sub>adj</sub> =1.3 [95%CI: 0.89, 2.0] in WHI Observational Study) and the risk of incident VT. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Washington Hospital Center |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Medicine/Endocrinology |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Sullivan, Shannon D |
| 790 ## - Authors |
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| All authors |
Allison MA, Blondon M, Cushman M, Harrington LB, Heckbert SR, Kaunitz AM, LaCroix AZ, McKnight B, Rossouw J, Smith NL, Sullivan S, Wang L, Woods NF |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1111/jth.13993">https://dx.doi.org/10.1111/jth.13993</a> |
| Public note |
https://dx.doi.org/10.1111/jth.13993 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
