Clinical effects of reported synthetic cannabinoid exposure in patients admitted to the intensive care unit. (Record no. 3693)

MARC details
000 -LEADER
fixed length control field 03976nam a22006377a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 180831s20192019 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0735-6757
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1016/j.ajem.2018.08.048 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code S0735-6757(18)30686-7 [pii]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 30146395
245 ## - TITLE STATEMENT
Title Clinical effects of reported synthetic cannabinoid exposure in patients admitted to the intensive care unit.
251 ## - Source
Source American Journal of Emergency Medicine. 37(6):1060-1064, 2019 Jun.
252 ## - Abbreviated Source
Abbreviated source Am J Emerg Med. 37(6):1060-1064, 2019 Jun.
253 ## - Journal Name
Journal name The American journal of emergency medicine
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2019
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2019
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status aheadofprint
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status ppublish
266 ## - Date added to catalog
Date added to catalog 2018-08-31
501 ## - WITH NOTE
Local holdings Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006
520 ## - SUMMARY, ETC.
Abstract CONCLUSIONS: Patients admitted to ICU after SC exposure exhibit significant organ dysfunction, particularly neurologic and respiratory. Prognosis is good with supportive care.
520 ## - SUMMARY, ETC.
Abstract Copyright (c) 2018. Published by Elsevier Inc.
520 ## - SUMMARY, ETC.
Abstract DESIGN: Retrospective case series of patients admitted to medical or cardiac ICU.
520 ## - SUMMARY, ETC.
Abstract MEASUREMENTS: Demographics, Sequential Organ Failure Assessment (SOFA) scores, and clinical parameters documenting the effects and hospital course.
520 ## - SUMMARY, ETC.
Abstract OBJECTIVE: To characterize the clinical presentation and hospital course of patients with reported synthetic cannabinoid (SC) exposure requiring Intensive Care Unit (ICU) admission.
520 ## - SUMMARY, ETC.
Abstract PARTICIPANTS: Adults >=18years old admitted from the emergency department (ED) in 2015.
520 ## - SUMMARY, ETC.
Abstract RESULTS: 23 patients met inclusion criteria. Median age was 47years (interquartile range [IQR], 32-54); 83% male; 78% black. Patients were generally tachycardic (HR>100), (65%) and hypertensive (SBP>140), (65%) on admission. The initial chest X-ray and ECG were abnormal in 43% and 68% of patients, respectively. Pulmonary edema and tachycardia were the most common findings. Head CT imaging was abnormal in 5% of patients. Troponin was elevated >1.0ng/ml in 3 of 19 patients (16%). Other exposures detected on admission were marijuana (30%), alcohol (30%), and benzodiazepines (26%). The median SOFA score was 6 on admission and decreased over the next 3days. SOFA scores were primarily driven by altered neurologic status and respiratory failure. 91% required mechanical ventilation, 30% had seizures as a part of presentation, 18% required vasopressors, and 5% needed dialysis. Median hospital and ICU lengths of stay were 2.6 (IQR 1.4-3.5) and 1.6 (IQR 0.9-2.5) days, respectively. The median hospital charge was
Materials specified 7,008. All patients survived the index hospitalization.
520 ## - SUMMARY, ETC.
Abstract SETTING: Urban tertiary care center.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Cannabinoids/ae [Adverse Effects]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Synthetic Drugs/ae [Adverse Effects]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Adult
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Female
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Hospitalization/sn [Statistics & Numerical Data]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Intensive Care Units/og [Organization & Administration]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Intensive Care Units/sn [Statistics & Numerical Data]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Length of Stay/sn [Statistics & Numerical Data]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Male
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Middle Aged
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Pulmonary Edema/et [Etiology]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Retrospective Studies
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Severity of Illness Index
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Tachycardia/et [Etiology]
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Washington Hospital Center
656 ## - INDEX TERM--OCCUPATION
Department Emergency Medicine
656 ## - INDEX TERM--OCCUPATION
Department Medicine/Pulmonary-Critical Care
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Goyal, Munish
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Mazer-Amirshahi, Maryann
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Tatusov, Michael
790 ## - Authors
All authors Abbasi A, Goyal M, Mazer-Amirshahi M, Tatusov M
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1016/j.ajem.2018.08.048">https://dx.doi.org/10.1016/j.ajem.2018.08.048</a>
Public note https://dx.doi.org/10.1016/j.ajem.2018.08.048
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 08/31/2018   30146395 30146395 08/31/2018 08/31/2018 Journal Article

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