MARC details
000 -LEADER |
fixed length control field |
03075nam a22004937a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
181108s20182018 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
1661-7800 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
000493119 [pii] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1159/000493119 [doi] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
30384374 |
245 ## - TITLE STATEMENT |
Title |
Prescription Drug Shortages: Impact on Neonatal Intensive Care. |
251 ## - Source |
Source |
Neonatology. 115(2):108-115, 2018 Nov 01. |
252 ## - Abbreviated Source |
Abbreviated source |
Neonatology. 115(2):108-115, 2018 Nov 01. |
253 ## - Journal Name |
Journal name |
Neonatology |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2018 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2019 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
aheadofprint |
266 ## - Date added to catalog |
Date added to catalog |
2018-11-09 |
520 ## - SUMMARY, ETC. |
Abstract |
BACKGROUND: Prescription drug shortages have increased significantly during the past two decades and also impact drugs used in critical care and pediatrics. |
520 ## - SUMMARY, ETC. |
Abstract |
CONCLUSIONS: Drug shortages affected many agents used in NICUs, which can have quality and safety implications for patient care, especially in extremely low birth weight infants. Neonatologists must be aware of current shortages and implement mitigation strategies to optimize patient care. |
520 ## - SUMMARY, ETC. |
Abstract |
Copyright (c) 2018 S. Karger AG, Basel. |
520 ## - SUMMARY, ETC. |
Abstract |
METHODS: Drug shortage data for the top 100 NICU drugs were retrieved from the University of Utah Drug Information Service from 2001 to 2016. Data were analyzed focusing on drug class, formulation, reason for shortage, and shortage duration. |
520 ## - SUMMARY, ETC. |
Abstract |
OBJECTIVES: To analyze drug shortages affecting medications used in neonatal intensive care units (NICUs). |
520 ## - SUMMARY, ETC. |
Abstract |
RESULTS: Seventy-four of the top 100 NICU drugs were impacted by 227 shortages (10.3% of total shortages). Twenty-eight (12.3%) shortages were unresolved as of December 2016. Resolved shortages had a median duration of 8.8 months (interquartile range 3.6-21.3), and generic drugs were involved in 175 (87.9%). An alternative agent was available for 171 (85.8%) drugs but 120 (70.2%) of alternatives were also affected by shortages. Parenteral drugs were involved in 172 (86.4%) shortages, with longer durations than nonparenteral drugs (9.9 vs. 6.4 months, p = 0.022). The most common shortage reason was manufacturing problems (32.2%). |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Drugs, Generic/sd [Supply & Distribution] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Intensive Care Units, Neonatal/sn [Statistics & Numerical Data] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Intensive Care, Neonatal/st [Standards] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Prescription Drugs/sd [Supply & Distribution] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Humans |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Infant, Newborn |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Intensive Care Units, Neonatal/td [Trends] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Intensive Care, Neonatal/og [Organization & Administration] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Neonatologists |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
United States |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Washington Hospital Center |
656 ## - INDEX TERM--OCCUPATION |
Department |
Emergency Medicine |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Mazer-Amirshahi, Maryann |
790 ## - Authors |
All authors |
Fox E, Mazer-Amirshahi M, Samiee-Zafarghandy S, van den Anker JN, Ziesenitz VC, Zocchi M |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1159/000493119">https://dx.doi.org/10.1159/000493119</a> |
Public note |
https://dx.doi.org/10.1159/000493119 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |