MARC details
000 -LEADER |
fixed length control field |
03451nam a22003857a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
181108s20182018 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
0735-1097 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1016/j.jacc.2018.08.2163 [doi] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
S0735-1097(18)38383-9 [pii] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
30384885 |
245 ## - TITLE STATEMENT |
Title |
Healthy Behavior, Risk Factor Control, and Survival in the COURAGE Trial. |
251 ## - Source |
Source |
Journal of the American College of Cardiology. 72(19):2297-2305, 2018 Nov 06. |
252 ## - Abbreviated Source |
Abbreviated source |
J Am Coll Cardiol. 72(19):2297-2305, 2018 Nov 06. |
253 ## - Journal Name |
Journal name |
Journal of the American College of Cardiology |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2018 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2019 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
ppublish |
266 ## - Date added to catalog |
Date added to catalog |
2018-11-09 |
501 ## - WITH NOTE |
Local holdings |
Available online from MWHC library: 1995 - present, Available in print through MWHC library:1999-2007 |
520 ## - SUMMARY, ETC. |
Abstract |
BACKGROUND: Individual risk factor control improves survival in patients with stable ischemic heart disease (SIHD). It is uncertain if multiple risk factor control further extends survival. |
520 ## - SUMMARY, ETC. |
Abstract |
CONCLUSIONS: The greater the number of risk factors in control, the higher the probability of survival in patients with SIHD. More effective strategies are needed to achieve comprehensive risk factor control, including healthy behaviors. (Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation [COURAGE]; NCT00007657). |
520 ## - SUMMARY, ETC. |
Abstract |
Copyright (c) 2018 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved. |
520 ## - SUMMARY, ETC. |
Abstract |
METHODS: Of 2,287 participants in the COURAGE (Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation) trial, 2,102 (92%) had complete ascertainment of 6 pre-specified risk factors: systolic blood pressure, low-density lipoprotein cholesterol, smoking, physical activity, diet, and body mass index. Participants received interventions to control these risk factors. The outcome measure was mortality. |
520 ## - SUMMARY, ETC. |
Abstract |
OBJECTIVES: This study determined whether a greater number of risk factors at goal predicted improved survival in SIHD patients. |
520 ## - SUMMARY, ETC. |
Abstract |
RESULTS: During a mean follow-up of 6.8 years, 473 (22.5%) subjects died. In univariate analysis, the greater the number of risk factors controlled, the higher the probability of survival (unadjusted log rank: p < 0.001). In multivariate analysis, the strongest predictors at 1 year of improved survival were being a nonsmoker, regular physical activity, having a systolic blood pressure <130 mm Hg, and following the American Heart Association Step 2 diet. Baseline risk factor values and evidence-based medications did not independently predict survival once risk factor control at 1 year was included in the model. Having 4 to 6 risk factors compared with 0 to 1 risk factor at goal predicted lower mortality (hazard ratios for 4 and 6 controlled risk factors: 0.64; 95% confidence interval: 0.41 to 0.98, and 0.27; 95% confidence interval: 0.09 to 0.79, respectively). |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Heart & Vascular Institute |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Weintraub, William S |
790 ## - Authors |
All authors |
Berman DS, Boden WE, COURAGE Trial Group, Hartigan PM, Kostuk WJ, Mancini GBJ, Maron DJ, Sedlis SP, Spertus JA, Teo KK, Weintraub WS |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1016/j.jacc.2018.08.2163">https://dx.doi.org/10.1016/j.jacc.2018.08.2163</a> |
Public note |
https://dx.doi.org/10.1016/j.jacc.2018.08.2163 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |