MARC details
| 000 -LEADER |
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| fixed length control field |
02654nam a22003737a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
190314s20192019 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
0031-3998 |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1038/s41390-019-0311-1 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1038/s41390-019-0311-1 [pii] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
30700836 |
| 245 ## - TITLE STATEMENT |
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| Title |
In vivo textural and morphometric analysis of placental development in healthy & growth-restricted pregnancies using magnetic resonance imaging. |
| 251 ## - Source |
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| Source |
Pediatric Research. 2019 Jan 25 |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
Pediatr Res. 2019 Jan 25 |
| 253 ## - Journal Name |
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| Journal name |
Pediatric research |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2019 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2019 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
aheadofprint |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2019-03-14 |
| 501 ## - WITH NOTE |
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| Local holdings |
Available online through MWHC library: 1996 -2011 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
BACKGROUND: The objective of this study was to characterize structural changes in the healthy in vivo placenta by applying morphometric and textural analysis using magnetic resonance imaging (MRI), and to explore features that may be able to distinguish placental insufficiency in fetal growth restriction (FGR). |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSION: We report quantitative textural and morphometric changes in the in vivo placenta in healthy controls over the second half of pregnancy. These MRI features demonstrate important differences in placental development in the setting of placental insufficiency that relate to onset and severity of FGR, as well as neonatal outcome. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
METHODS: Women with healthy pregnancies or pregnancies complicated by FGR underwent MRI between 20 and 40 weeks gestation. Measures of placental morphometry (volume, elongation, depth) and digital texture (voxel-wise geometric and signal-intensity analysis) were calculated from T2W MR images. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
RESULTS: We studied 66 pregnant women (32 healthy controls, 34 FGR); during the study period, placentas undergo significant increases in size; signal intensity remains relatively constant, however there is increasing variation in spatial arrangements, suggestive of progressive microstructural heterogeneity. In FGR, placental size is smaller, with great homogeneity of signal intensity and spatial arrangements. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Washington Hospital Center |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Obstetrics and Gynecology/Maternal-Fetal Medicine |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Iqbal, Sara N |
| 790 ## - Authors |
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| All authors |
Andescavage N, Baschat A, Bulas D, Dahdouh S, Iqbal S, Jacobs M, Limperopoulos C, Yewale S |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1038/s41390-019-0311-1">https://dx.doi.org/10.1038/s41390-019-0311-1</a> |
| Public note |
https://dx.doi.org/10.1038/s41390-019-0311-1 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Journal Article |
| Item type description |
Article |
