Exceptional Response to Systemic Therapy in Advanced Metastatic Gastric Cancer: A Case Report. (Record no. 4122)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01902nam a22003377a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 190314s20162016 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 2168-8184 |
| 024 ## - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.7759/cureus.457 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER | |
| Standard number or code | PMC4752374 [pmc] |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| PMID | 26918225 |
| 245 ## - TITLE STATEMENT | |
| Title | Exceptional Response to Systemic Therapy in Advanced Metastatic Gastric Cancer: A Case Report. |
| 251 ## - Source | |
| Source | Cureus. 8(1):e457, 2016 Jan 12. |
| 252 ## - Abbreviated Source | |
| Abbreviated source | Cureus. 8(1):e457, 2016 Jan 12. |
| 253 ## - Journal Name | |
| Journal name | Cureus |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Year | 2016 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Manufacturer | FY2016 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] | |
| Publication status | epublish |
| 266 ## - Date added to catalog | |
| Date added to catalog | 2019-03-14 |
| 520 ## - SUMMARY, ETC. | |
| Abstract | Gastroesophageal adenocarcinomas represent one of the top five most common types of cancer worldwide. Despite significant advancement, it is still not known which first-line chemotherapy option is best matched to an individual patient. The vast advances in molecular biology have led to the discovery of many potential predictive biomarkers, such as HER-2 neu, thymidylate synthase (TS), excision repair cross-complementation group 1 (ERCC1), and topoisomerase-1 (TOPO1). These markers could allow us to select treatment based on an individual's tumor profile, resulting in an improvement of outcome. Our report highlights two patients with metastatic gastric cancer that achieved an exceptional response with traditional therapy and provides insights into the future perspectives of molecular profile-directed chemotherapy. |
| 546 ## - LANGUAGE NOTE | |
| Language note | English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | PubMed-not-MEDLINE -- Not indexed |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME | |
| Institution | MedStar Medical Group |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME | |
| Institution | Washington Cancer Institute |
| 657 ## - INDEX TERM--FUNCTION | |
| Medline publication type | Case Reports |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Local Authors | Colton, Bradley |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Local Authors | Manning, Maria A |
| 790 ## - Authors | |
| All authors | Carroll JE, Colton B, Hartley M, Manning MA, Mikhail S, Salem ME, Smaglo BG, Xiu J |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| DOI | <a href="https://dx.doi.org/10.7759/cureus.457">https://dx.doi.org/10.7759/cureus.457</a> |
| Public note | https://dx.doi.org/10.7759/cureus.457 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Item type description | Article |
| Withdrawn status | Lost status | Damaged status | Not for loan | Collection | Home library | Current library | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MedStar Authors Catalog | MedStar Authors Catalog | 03/14/2019 | 26918225 | 26918225 | 03/14/2019 | 03/14/2019 | Journal Article |