MARC details
| 000 -LEADER |
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| fixed length control field |
03335nam a22003737a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
190314s20152015 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
2000-9666 |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.3402/jchimp.v5.29624 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
29624 [pii] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
PMC4677584 [pmc] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
26653696 |
| 245 ## - TITLE STATEMENT |
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| Title |
When a pulmonary embolism is not a pulmonary embolism: a rare case of primary pulmonary leiomyosarcoma. |
| 251 ## - Source |
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| Source |
Journal of Community Hospital Internal Medicine Perspectives. 5(6):29624, 2015. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
J Community Hosp Intern Med Perspect. 5(6):29624, 2015. |
| 253 ## - Journal Name |
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| Journal name |
Journal of community hospital internal medicine perspectives |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2015 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2016 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
epublish |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2019-03-14 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Arterial leiomyosarcomas account for up to 21% of vascular leiomyosarcomas, with 56% of arterial leiomyosarcomas occurring in the pulmonary artery. While isolated cases of primary pulmonary artery leiomyosarcoma document survival up to 36 months after treatment, these uncommon, aggressive tumors are highly lethal, with 1-year survival estimated at 20% from the onset of symptoms. We discuss a rare case of a pulmonary artery leiomyosarcoma that was originally diagnosed as a pulmonary embolism (PE). A 72-year-old Caucasian female was initially diagnosed with 'saddle pulmonary embolism' based on computerized tomographic angiography of the chest 2 months prior to admission and placed on anticoagulation. Dyspnea escalated, and serial computed tomography scans showed cardiomegaly with pulmonary emboli involving the right and left main pulmonary arteries with extension into the right and left upper and lower lobe branches. An echocardiogram on admission showed severe pulmonary hypertension with a pulmonary artery pressure of 82.9 mm Hg, and a severely enlarged right ventricle. Respiratory distress and multiorgan failure developed and, unfortunately, the patient expired. Autopsy showed a lobulated, yellow mass throughout the main pulmonary arteries measuring 13 cm in diameter. The mass extended into the parenchyma of the right upper lobe. On microscopy, the mass was consistent with a high-grade primary pulmonary artery leiomyosarcoma. Median survival of patients with primary pulmonary artery leiomyosarcoma without surgery is one and a half months, and mortality is usually due to right-sided heart failure. Pulmonary artery leiomyosarcoma is a rare but highly lethal disease commonly mistaken for PE. Thus, we recommend clinicians to suspect this malignancy when anticoagulation fails to relieve initial symptoms. In conclusion, early detection and suspicion of pulmonary artery leiomyosarcoma should be considered in patients refractory to anticoagulation, prompting initiation of early intervention. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
PubMed-not-MEDLINE -- Not indexed |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
Medstar Franklin Square Medical Center |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Medicine |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Pulmonary and Critical Care Medicine |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Case Reports |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Dahagam, Chanukya R |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Muganlinskaya, Nargiz |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Selinger, Stephen |
| 790 ## - Authors |
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| All authors |
Dahagam C, Guzman A, Muganlinskaya N, Selinger SR |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.3402/jchimp.v5.29624">https://dx.doi.org/10.3402/jchimp.v5.29624</a> |
| Public note |
https://dx.doi.org/10.3402/jchimp.v5.29624 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
