Fiducial marker placement with electromagnetic navigation bronchoscopy: a subgroup analysis of the prospective, multicenter NAVIGATE study. (Record no. 4281)

MARC details
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fixed length control field 03302nam a22003857a 4500
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fixed length control field 190521s20192019 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1753-4658
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1177/1753466619841234 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code PMC6454637 [pmc]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 30958102
245 ## - TITLE STATEMENT
Title Fiducial marker placement with electromagnetic navigation bronchoscopy: a subgroup analysis of the prospective, multicenter NAVIGATE study.
251 ## - Source
Source Therapeutic Advances in Respiratory Disease. 13:1753466619841234, 2019 Jan-Dec.
252 ## - Abbreviated Source
Abbreviated source Therap. adv. respir. dis.. 13:1753466619841234, 2019 Jan-Dec.
253 ## - Journal Name
Journal name Therapeutic advances in respiratory disease
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2019
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2019
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status ppublish
266 ## - Date added to catalog
Date added to catalog 2019-05-21
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: Fiducial markers (FMs) help direct stereotactic body radiation therapy (SBRT) and localization for surgical resection in lung cancer management. We report the safety, accuracy, and practice patterns of FM placement utilizing electromagnetic navigation bronchoscopy (ENB).
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Abstract CONCLUSION: ENB is an accurate and versatile tool to place FMs for SBRT and localization for surgical resection with low complication rates. The ability to perform a biopsy safely in the same procedure can also increase efficiency. The impact of practice pattern variations on therapeutic effectiveness requires further study.
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Abstract METHODS: NAVIGATE is a global, prospective, multicenter, observational cohort study of ENB using the superDimensionTM navigation system. This prospectively collected subgroup analysis presents the patient demographics, procedural characteristics, and 1-month outcomes in patients undergoing ENB-guided FM placement. Follow up through 24 months is ongoing.
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Abstract RESULTS: Two-hundred fifty-eight patients from 21 centers in the United States were included. General anesthesia was used in 68.2%. Lesion location was confirmed by radial endobronchial ultrasound in 34.5% of procedures. The median ENB procedure time was 31.0 min. Concurrent lung lesion biopsy was conducted in 82.6% (213/258) of patients. A mean of 2.2 +/- 1.7 FMs (median 1.0 FMs) were placed per patient and 99.2% were accurately positioned based on subjective operator assessment. Follow-up imaging showed that 94.1% (239/254) of markers remained in place. The procedure-related pneumothorax rate was 5.4% (14/258) overall and 3.1% (8/258) grade 2 based on the Common Terminology Criteria for Adverse Events scale. The procedure-related grade 4 respiratory failure rate was 1.6% (4/258). There were no bronchopulmonary hemorrhages.
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Abstract TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT02410837.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Franklin Square Medical Center
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Department Angelos Center for Lung Disease
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Medline publication type Journal Article
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Medline publication type Research Support, Non-U.S. Gov't
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Local Authors Krimsky, William S
790 ## - Authors
All authors Anciano CJ, Bowling MR, Folch EE, Kazakov J, Khandhar SJ, Krimsky WS, LeMense GP, Linden PA, Murillo BA, Nead MA, Pritchett MA, Teba CV, Towe CW, Williams T
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1177/1753466619841234">https://dx.doi.org/10.1177/1753466619841234</a>
Public note https://dx.doi.org/10.1177/1753466619841234
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
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          MedStar Authors Catalog MedStar Authors Catalog 05/21/2019   30958102 30958102 05/21/2019 05/21/2019 Journal Article

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