MARC details
| 000 -LEADER |
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| fixed length control field |
03870nam a22006137a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
190827s20192019 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
1876-4789 |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1016/j.jacl.2019.07.004 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
S1933-2874(19)30236-3 [pii] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
31427271 |
| 245 ## - TITLE STATEMENT |
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| Title |
The economic burden of hypertriglyceridemia among US adults with diabetes or atherosclerotic cardiovascular disease on statin therapy. |
| 251 ## - Source |
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| Source |
Journal of Clinical Lipidology. 13(5):754-761, 2019 Sep - Oct. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
J. clin. lipidol.. 13(5):754-761, 2019 Sep - Oct. |
| 252 ## - Abbreviated Source |
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| Former abbreviated source |
J. clin. lipidol.. 2019 Jul 20 |
| 253 ## - Journal Name |
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| Journal name |
Journal of clinical lipidology |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2019 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2020 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
aheadofprint |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
ppublish |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2019-08-27 |
| 268 ## - Previous citation |
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| -- |
Journal of Clinical Lipidology. 2019 Jul 20 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
BACKGROUND: Hypertriglyceridemia (HTG) is associated with increased cardiovascular disease (CVD) risk. However, the cost burden of HTG-related CVD in high-risk US adults on statins has not been well characterized. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSION: In US adults on statins and at high risk for CVD, the health care costs associated with HTG are substantial. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Copyright (c) 2019 National Lipid Association. Published by Elsevier Inc. All rights reserved. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
METHODS: We estimated population sizes and annual health care costs among US adults aged >=45 years with diabetes or CVD taking statin therapy with normal triglycerides (TGs) defined as TG < 150 mg/dL compared with those with HTG defined as TG >= 150 mg/dL. Population sizes were estimated from the 2007-2014 National Health and Nutrition Examination Surveys. Adjusted mean total annual health care costs in 2015 US dollars were estimated using the Optum Research Database. The annual total health care cost burden was estimated by multiplying the population size by the mean annual total incremental health care costs overall and within subgroups. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
OBJECTIVE: We estimated the HTG-related health care cost burden among US adults with CVD or diabetes taking statin therapy. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
RESULTS: There were 6.2 (95% confidence interval [CI], 5.4 - 7.1) million and 12.0 (95% CI, 11.1 - 12.9) million US adults aged >=45 years with diabetes and/or CVD on statin therapy with TG >= 150 mg/dL and TG < 150 mg/dL, respectively. The mean adjusted incremental total one-year health care costs in adults with TG >= 150 mg/dL compared with those with TG < 150 mg/dL was |
| -- |
730 (95% CI, |
| -- |
160 - |
| Source |
320). This leads to a projected annual incremental cost burden associated with HTG in patients with diabetes or CVD on statins of |
| -- |
0.7 billion (95% CI, |
| Linkage |
.8 B - |
| -- |
4.6 B). |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Atherosclerosis/dt [Drug Therapy] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Atherosclerosis/ec [Economics] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Cardiovascular Diseases/ec [Economics] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Cost of Illness |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Diabetes Mellitus/ec [Economics] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Hydroxymethylglutaryl-CoA Reductase Inhibitors/ec [Economics] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Hydroxymethylglutaryl-CoA Reductase Inhibitors/tu [Therapeutic Use] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Hypertriglyceridemia/ec [Economics] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Adult |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Aged |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Female |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Health Care Costs |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Humans |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Male |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Middle Aged |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
United States/ep [Epidemiology] |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Heart & Vascular Institute |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Case, Brian C |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Kolm, Paul |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Weintraub, William S |
| 790 ## - Authors |
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| All authors |
Bress AP, Case BC, Fan W, Granowitz CB, Herrick JS, Hull M, Kolm P, Philip S, Toth PP, Weintraub WS, Wong ND |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1016/j.jacl.2019.07.004">https://dx.doi.org/10.1016/j.jacl.2019.07.004</a> |
| Public note |
https://dx.doi.org/10.1016/j.jacl.2019.07.004 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
