MARC details
000 -LEADER |
fixed length control field |
03703nam a22003737a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
191010s20192019 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
0735-1097 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1016/j.jacc.2019.06.058 [doi] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
S0735-1097(19)35840-1 [pii] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
31466616 |
245 ## - TITLE STATEMENT |
Title |
Anticoagulation After Surgical or Transcatheter Bioprosthetic Aortic Valve Replacement. |
251 ## - Source |
Source |
Journal of the American College of Cardiology. 74(9):1190-1200, 2019 Sep 03. |
252 ## - Abbreviated Source |
Abbreviated source |
J Am Coll Cardiol. 74(9):1190-1200, 2019 Sep 03. |
253 ## - Journal Name |
Journal name |
Journal of the American College of Cardiology |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2019 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2020 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
ppublish |
266 ## - Date added to catalog |
Date added to catalog |
2019-10-10 |
501 ## - WITH NOTE |
Local holdings |
Available online from MWHC library: 1995 - present, Available in print through MWHC library:1999-2007 |
520 ## - SUMMARY, ETC. |
Abstract |
BACKGROUND: There is paucity of evidence on the impact of anticoagulation (AC) after bioprosthetic aortic valve replacement (AVR) on valve hemodynamics and clinical outcomes. |
520 ## - SUMMARY, ETC. |
Abstract |
CONCLUSIONS: In the short term, early AC after bioprosthetic AVR did not result in adverse clinical events, did not significantly affect aortic valve hemodynamics (aortic valve gradients or area), and was associated with decreased rates of stroke after SAVR (but not after TAVR). Whether early AC after bioprosthetic AVR has impact on long-term outcomes remains to be determined. (Placement of AoRTic TraNscathetER Valves [PARTNERII A]; NCT01314313). Copyright (c) 2019. Published by Elsevier Inc. |
520 ## - SUMMARY, ETC. |
Abstract |
METHODS: Data on antiplatelet and antithrombotic therapy were collected. Echocardiograms were performed at 30 days and 1 year post-AVR. Linear regression model and propensity-score adjusted cox proportional model were used to assess the impact of AC on valve hemodynamics and clinical outcomes, respectively. |
520 ## - SUMMARY, ETC. |
Abstract |
OBJECTIVES: The study aimed to assess the impact of AC after bioprosthetic AVR on valve hemodynamics and clinical outcomes. |
520 ## - SUMMARY, ETC. |
Abstract |
RESULTS: A total of 4,832 patients undergoing bioprosthetic AVR (transcatheter aortic valve replacement [TAVR], n = 3,889 and surgical AVR [SAVR], n = 943) in the pooled cohort of PARTNER2 (Placement of Aortic Transcatheter Valves) randomized trials and nonrandomized registries were studied. Following adjustment for valve size, annular diameter, atrial fibrillation, and ejection fraction at the time of assessment of hemodynamics, there was no significant difference in aortic valve mean gradients or aortic valve areas between patients discharged on AC vs. those not discharged on AC, for either TAVR or SAVR cohorts. A significantly greater proportion of patients not discharged on AC had an increase in mean gradient >10 mm Hg from 30 days to 1 year, compared with those discharged on AC (2.3% vs. 1.1%, p = 0.03). There was no independent association between AC after TAVR and adverse outcomes (death, p = 0.15; rehospitalization, p = 0.16), whereas AC after SAVR was associated with significantly fewer strokes (hazard ratio [HR]: 0.17; 95% confidence interval [CI]: 0.05-0.60; p = 0.006). |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Heart & Vascular Institute |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Thourani, Vinod H |
790 ## - Authors |
All authors |
Abramowitz Y, Alu MC, Babaliaros VC, Chakravarty T, Cheng W, Douglas PS, Hahn RT, Herrmann HC, Kapadia S, Kereiakes D, Kodali S, Leon MB, Liu Y, Mack M, Makkar RR, McAndrew T, Patel A, Raschpichler M, Smalling RW, Svensson L, Szeto WY, Thourani VH, Yoon SH |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1016/j.jacc.2019.06.058">https://dx.doi.org/10.1016/j.jacc.2019.06.058</a> |
Public note |
https://dx.doi.org/10.1016/j.jacc.2019.06.058 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |