MARC details
| 000 -LEADER |
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| fixed length control field |
08039nam a22006737a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
191014s20192019 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
0012-3706 |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1097/DCR.0000000000001486 [doi] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
31567924 |
| 245 ## - TITLE STATEMENT |
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| Title |
Implementation of an Enhanced Recovery Protocol Is Associated With On-Time Initiation of Adjuvant Chemotherapy in Colorectal Cancer. |
| 251 ## - Source |
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| Source |
Diseases of the Colon & Rectum. 62(11):1305-1315, 2019 Nov. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
Dis Colon Rectum. 62(11):1305-1315, 2019 Nov. |
| 253 ## - Journal Name |
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| Journal name |
Diseases of the colon and rectum |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2019 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2020 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
ppublish |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2019-10-14 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
BACKGROUND: Delayed initiation of adjuvant chemotherapy negatively impacts long-term survival in patients with colorectal cancer. Colorectal enhanced recovery protocols result in decreased complications and length of stay; however, the impact of enhanced recovery on the timing of adjuvant chemotherapy remains unknown. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSIONS: Enhanced recovery was associated with receiving on-time adjuvant chemotherapy. As prompt initiation of adjuvant chemotherapy improves survival in colorectal cancer, future investigation of long-term oncologic outcomes is necessary to evaluate the potential impact of enhanced recovery on survival. See Video Abstract at http://links.lww.com/DCR/B21. LA IMPLEMENTACION DE UN PROTOCOLO DE RECUPERACION ACELERADA SE ASOCIA CON EL INICIO A TIEMPO DE QUIMIOTERAPIA ADYUVANTE EN CANCER COLORRECTAL:: El inicio tardio de la quimioterapia adyuvante afecta negativamente la supervivencia a largo plazo en pacientes con cancer colorrectal. Los protocolos de recuperacion acelerada colorrectales dan lugar a una disminucion de las complicaciones y la duracion de estancia hospitalaria; sin embargo, el impacto de la recuperacion acelerada en el momento de inicio de quimioterapia adyuvante sigue siendo desconocido.Este estudio tuvo como objetivo identificar los factores asociados con la administracion a tiempo de la quimioterapia adyuvante despues de la cirugia de cancer colorrectal, con la hipotesis de que la implementacion de un protocolo de recuperacion acelerada daria lugar a que mas pacientes reciban quimioterapia a tiempo.Estudio de cohorte retrospectivo que compara la tasa de administracion de quimioterapia adyuvante a tiempo despues de la reseccion del cancer colorrectal antes y despues de la implementacion de un protocolo de recuperacion acelerada.Centro medico academico grande.Todos los pacientes que se sometieron a resecciones de cancer colorrectal no emergentes con intencion curativa desde enero de 2010 hasta junio de 2017, excluyendo a los pacientes que no tenian indicacion de quimioterapia adyuvante, que recibieron quimioterapia sistemica preoperatoria o no tenian registros medicos de oncologia disponibles.Los pacientes se compararon antes y despues de la implementacion de la recuperacion acelerada, con la tasa de administracion de quimioterapia adyuvante a tiempo como el resultado primario. La administracion de quimioterapia adyuvante se considero a tiempo si se inicio <=8 semanas despues de la operacion, y el tratamiento se considero retrasado / omitido si se inicio> 8 semanas despues de la operacion (retrasado) o nunca fue recibido (omitido). La regresion logistica multivariable identifico predictores de administracion de quimioterapia a tiempo.363 pacientes cumplieron con los criterios de inclusion, con 189 (52.1%) pacientes sometidos a cirugia despues de la implementacion de recuperacion acelerada. Los grupos difirieron en el abordaje laparoscopico y la duracion media del procedimiento; ambos factores fueron mayores despues de la recuperacion acelerada. Significativamente mas pacientes recibieron quimioterapia a tiempo despues de la implementacion de recuperacion acelerada (p = 0.007). La recuperacion acelerada fue un factor predictivo independiente de quimioterapia adyuvante a tiempo (p = 0.014).Diseno retrospectivo, tipo antes y despues no aleatorizado.La recuperacion acelerada se asocio con la recepcion de quimioterapia adyuvante a tiempo. Debido a que el inicio rapido de la quimioterapia adyuvante mejora la supervivencia en el cancer colorrectal, en el futuro sera necesario investigar los resultados oncologicos a largo plazo para evaluar el impacto potencial de la recuperacion acelerada en la supervivencia. Vea el Resumen en Video en http://links.lww.com/DCR/B21. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
DESIGN: This was a retrospective cohort study comparing the rate of on-time adjuvant chemotherapy delivery after colorectal cancer resection before and after implementation of an enhanced recovery protocol. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
LIMITATIONS: The study was limited by its retrospective and nonrandomized before-and-after design. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
MAIN OUTCOME MEASURES: Patients before and enhanced recovery were compared, with the rate of on-time adjuvant chemotherapy delivery as the primary outcome. Adjuvant chemotherapy delivery was considered on time if initiated <=8 weeks postoperatively, and treatment was considered delayed or omitted if initiated >8 weeks postoperatively (delayed) or never received (omitted). Multivariable logistic regression identified predictors of on-time chemotherapy delivery. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
OBJECTIVE: This study aimed to identify factors associated with on-time delivery of adjuvant chemotherapy after colorectal cancer surgery, hypothesizing that implementation of an enhanced recovery protocol would result in more patients receiving on-time chemotherapy. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
PATIENTS: All of the patients who underwent nonemergent colorectal cancer resections for curative intent from January 2010 to June 2017, excluding patients who had no indication for adjuvant chemotherapy, had received preoperative systemic chemotherapy, or did not have medical oncology records available were included. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
RESULTS: A total of 363 patients met inclusion criteria, with 189 patients (52.1%) undergoing surgery after enhanced recovery implementation. Groups differed in laparoscopic approach and median procedure duration, both of which were higher after enhanced recovery. Significantly more patients received on-time chemotherapy after enhanced recovery implementation (p = 0.007). Enhanced recovery was an independent predictor of on-time adjuvant chemotherapy (p = 0.014). |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
SETTINGS: The study was conducted at a large academic medical center. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Antineoplastic Agents/tu [Therapeutic Use] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Chemotherapy, Adjuvant/mt [Methods] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Colectomy/rh [Rehabilitation] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Colorectal Neoplasms |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Postoperative Complications/pc [Prevention & Control] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Recovery of Function/de [Drug Effects] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Survivors/sn [Statistics & Numerical Data] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Time-to-Treatment |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Clinical Protocols/st [Standards] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Colectomy/mt [Methods] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Colorectal Neoplasms/ep [Epidemiology] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Colorectal Neoplasms/pa [Pathology] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Colorectal Neoplasms/rh [Rehabilitation] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Colorectal Neoplasms/th [Therapy] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Female |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Humans |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Length of Stay/sn [Statistics & Numerical Data] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Male |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Middle Aged |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Retrospective Studies |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Time-to-Treatment/sn [Statistics & Numerical Data] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Time-to-Treatment/st [Standards] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
United States/ep [Epidemiology] |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Washington Hospital Center |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Medicine/Internal Medicine |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Bauer-Nilsen, Kristine |
| 790 ## - Authors |
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| All authors |
Bauer-Nilsen K, Friel CM, Hassinger TE, Hedrick TL, Hoang SC, Martin AN, Mehaffey JH, Reilley MJ, Sarosiek BM, Thiele RH, Turrentine FE |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1097/DCR.0000000000001486">https://dx.doi.org/10.1097/DCR.0000000000001486</a> |
| Public note |
https://dx.doi.org/10.1097/DCR.0000000000001486 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
