MARC details
000 -LEADER |
fixed length control field |
02519nam a22003497a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
191204s20192019 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
1071-9164 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1016/j.cardfail.2019.10.013 [doi] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
S1071-9164(19)30502-0 [pii] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
31704196 |
245 ## - TITLE STATEMENT |
Title |
Outcomes of Severely Obese Patients Supported by a Centrifugal-Flow Left Ventricular Assist Device. |
251 ## - Source |
Source |
Journal of Cardiac Failure. 2019 Nov 05 |
252 ## - Abbreviated Source |
Abbreviated source |
J Card Fail. 2019 Nov 05 |
253 ## - Journal Name |
Journal name |
Journal of cardiac failure |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2019 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2020 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
aheadofprint |
266 ## - Date added to catalog |
Date added to catalog |
2019-12-04 |
520 ## - SUMMARY, ETC. |
Abstract |
BACKGROUND: Ventricular assist devices provide improved outcomes for advanced heart failure patients, but their benefit in the severely obese is not well documented. |
520 ## - SUMMARY, ETC. |
Abstract |
CONCLUSIONS: Despite an increased risk of adverse events, severe obesity was not associated with reduced survival or quality of life. A better understanding of the risks and benefits of LVAD therapy in obese patients will help in the shared decision-making of the patient selection process. Copyright (c) 2019. Published by Elsevier Inc. |
520 ## - SUMMARY, ETC. |
Abstract |
METHODS: Patients enrolled in the HeartWare ADVANCE trial (n=382) were divided into two body mass index (BMI) groups. Patients with severe obesity (> 35 kg/m2) were compared to a control group with BMI <= 35 kg/m2. The association of BMI with survival was tested using Kaplan-Meier analysis and major adverse events were compared. |
520 ## - SUMMARY, ETC. |
Abstract |
RESULTS: At implantation, 48 (13%) of patients were severely obese. There was no difference in survival through two years of support between severely obese patients and the control group. Severely obese patients were at higher risk of driveline infection (p=0.01) and acute renal dysfunction (p=0.002). Both groups experienced similar improvements in quality of life. Functional capacity improved in both severely obese and control patients, although severely obese patients had smaller improvements than controls in their six-minute walk scores. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Heart & Vascular Institute |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Najjar, Samer S |
790 ## - Authors |
All authors |
Birks EJ, Ewald GA, Kiernan MS, Leadley K, Najjar SS, Patel CB, Uriel N, Vest AR |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1016/j.cardfail.2019.10.013">https://dx.doi.org/10.1016/j.cardfail.2019.10.013</a> |
Public note |
https://dx.doi.org/10.1016/j.cardfail.2019.10.013 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |