The prognostic value of regadenoson SPECT myocardial perfusion imaging: The largest cohort to date. (Record no. 5061)

MARC details
000 -LEADER
fixed length control field 03212nam a22005297a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200709s20202020 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1071-3581
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/s12350-020-02135-y [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/s12350-020-02135-y [pii]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 32383079
245 ## - TITLE STATEMENT
Title The prognostic value of regadenoson SPECT myocardial perfusion imaging: The largest cohort to date.
251 ## - Source
Source Journal of Nuclear Cardiology. 28(6):2799-2807, 2021 12.
252 ## - Abbreviated Source
Abbreviated source J Nucl Cardiol. 28(6):2799-2807, 2021 12.
252 ## - Abbreviated Source
Former abbreviated source J Nucl Cardiol. 2020 May 07
253 ## - Journal Name
Journal name Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2021
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2020
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status ppublish
266 ## - Date added to catalog
Date added to catalog 2020-07-09
268 ## - Previous citation
-- Journal of Nuclear Cardiology. 2020 May 07
501 ## - WITH NOTE
Local holdings Available online from MWHC library: 1995 - present
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: Data on the prognostic value of regadenoson SPECT myocardial perfusion imaging (MPI) is limited and based on small cohorts.
520 ## - SUMMARY, ETC.
Abstract CONCLUSION: In the largest cohort to date, we demonstrated that the presence and severity of perfusion abnormality and myocardial ischemia on regadenoson stress SPECT-MPI are associated with an independent increase in MACE.
520 ## - SUMMARY, ETC.
Abstract METHODS AND RESULTS: We conducted a single-center, retrospective cohort study of 10,275 consecutive patients who underwent regadenoson SPECT-MPI. Among the study subjects, 28.7% had abnormal MPI and 25.5% had myocardial ischemia. Patients were followed for a mean of 2.4 +/- 2.2 years for major adverse cardiac events (MACE), defined as cardiac death or myocardial infarction. There was a significant stepwise increase in MACE with an increasing burden of perfusion abnormality (P < .001) and myocardial ischemia (P < .001). Abnormal MPI (adjusted HR 1.52; 95% CI 1.21 to 1.91) and myocardial ischemia (adjusted HR 1.53; 95% CI 1.25 to 1.89) were associated with MACE, independent of and incremental to clinical covariates and left ventricular ejection fraction (LVEF). Moreover, post-stress LVEF, LVEF reserve, and left ventricular end-diastolic volume added significant prognostic information. Transient ischemic dilation >= 1.31 did not provide incremental prognostic value (adjusted HR 1.02; P = .906).
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Myocardial Perfusion Imaging/mt [Methods]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Purines
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Pyrazoles
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Tomography, Emission-Computed, Single-Photon/mt [Methods]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aged
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cohort Studies
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Female
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Male
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Middle Aged
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Myocardial Infarction/dg [Diagnostic Imaging]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Myocardial Ischemia/dg [Diagnostic Imaging]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Prognosis
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Retrospective Studies
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Union Memorial Hospital
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Khan, Rozi
790 ## - Authors
All authors Diep L, Doukky R, Iskander F, Iskander M, Kattoor AJ, Khan R, Kolkailah AA
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1007/s12350-020-02135-y">https://dx.doi.org/10.1007/s12350-020-02135-y</a>
Public note https://dx.doi.org/10.1007/s12350-020-02135-y
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 07/09/2020   32383079 32383079 07/09/2020 07/09/2020 Journal Article

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