Postprocedural Pain Associated With 5 Versus 20 Intradetrusor Injections of onabotulinumtoxinA for Treatment of Overactive Bladder: A Multicenter Randomized Clinical Trial. (Record no. 527)

MARC details
000 -LEADER
fixed length control field 03479nam a22004097a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 220706s20222022 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 2151-8378
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 01436319-990000000-00027 [pii]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1097/SPV.0000000000001199 [doi]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 35543540
245 ## - TITLE STATEMENT
Title Postprocedural Pain Associated With 5 Versus 20 Intradetrusor Injections of onabotulinumtoxinA for Treatment of Overactive Bladder: A Multicenter Randomized Clinical Trial.
251 ## - Source
Source Female Pelvic Medicine & Reconstructive Surgery. 2022 May 12
252 ## - Abbreviated Source
Abbreviated source Female pelvic med. reconstr. surg.. 2022 May 12
253 ## - Journal Name
Journal name Female pelvic medicine & reconstructive surgery
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2022
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2022
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Publication date 2022 May 12
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status aheadofprint
266 ## - Date added to catalog
Date added to catalog 2022-07-06
520 ## - SUMMARY, ETC.
Abstract CONCLUSIONS: Perceived pain, efficacy, and postprocedure complications did not significantly differ between patients receiving 5 injections and 20 injections, but procedure time was significantly shorter. Copyright © 2022 American Urogynecologic Society. All rights reserved.
520 ## - SUMMARY, ETC.
Abstract IMPORTANCE: Intradetrusor injection of onabotulinumtoxinA is performed via varying injection paradigms but no studies have studied the various effects of these paradigms on patient experience with the procedure.
520 ## - SUMMARY, ETC.
Abstract OBJECTIVES: This randomized clinical trial aims to compare pain and procedure time between patients receiving a 100-unit dose of onabotulinumtoxinA in 5 injections compared to 20 injections for the treatment of idiopathic overactive bladder or urgency urinary incontinence.
520 ## - SUMMARY, ETC.
Abstract RESULTS: The average pain score was not statistically significant between groups (2; interquartile range, 1-4 for the 5 injection group vs 3; interquartile range, 2-4 for the 20 injection group; P = 0.27). Patients who received 5 injections experienced significantly shorter mean procedure time as compared with patients who received 20 injections (76 seconds vs 176 seconds; P < 0.001). There were no differences in subjective efficacy or adverse events between groups.
520 ## - SUMMARY, ETC.
Abstract STUDY DESIGN: Patients presenting with refractory overactive bladder or urgency urinary incontinence at 2 clinical sites were identified and randomized to undergo onabotulinumtoxinA treatment with 5 injections versus 20 injections. Patients rated their pain level on a 10-point visual analog scale at procedure completion. The procedure duration was recorded with a stopwatch. Patients were followed up 6 weeks postprocedure, at which time they completed a Global Response Assessment to determine subjective efficacy of treatment. Participants were additionally monitored for incidence of adverse events in the follow-up period.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Washington Hospital Center
656 ## - INDEX TERM--OCCUPATION
Department Female Pelvic Medicine & Reconstructive Surgery Fellowship
656 ## - INDEX TERM--OCCUPATION
Department Obstetrics and Gynecology/Female Pelvic Medicine and Reconstructive Surgery
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Iglesia, Cheryl
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Woodburn, Katherine
Institution Code MedStar Washington Hospital Center
Program Female Pelvic Medicine & Reconstructive Surgery Fellowship
790 ## - Authors
All authors Bassaly R, Chang ES, Greene K, Iglesia C, Ringel N, Tanner JP, Woodburn KL, Wyman A
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1097/SPV.0000000000001199">https://dx.doi.org/10.1097/SPV.0000000000001199</a>
Public note https://dx.doi.org/10.1097/SPV.0000000000001199
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 07/06/2022   35543540 35543540 07/06/2022 07/06/2022 Journal Article

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