MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03828nam a22006377a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
200902s20202020 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
|---|
| International Standard Serial Number |
0090-4295 |
| 024 ## - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
10.1016/j.urology.2020.06.087 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
S0090-4295(20)30992-4 [pii] |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
|---|
| PMID |
32810481 |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
Sex and Racial Disparities in the Treatment and Outcomes of Muscle-invasive Bladder Cancer. |
| 251 ## - Source |
|---|
| Source |
Urology. 151:154-162, 2021 05. |
| 252 ## - Abbreviated Source |
|---|
| Abbreviated source |
Urology. 151:154-162, 2021 05. |
| 252 ## - Abbreviated Source |
|---|
| Former abbreviated source |
Urology. 2020 Aug 15 |
| 253 ## - Journal Name |
|---|
| Journal name |
Urology |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Year |
2021 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Manufacturer |
FY2021 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
|---|
| Publication status |
aheadofprint |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
|---|
| Publication status |
ppublish |
| 266 ## - Date added to catalog |
|---|
| Date added to catalog |
2020-09-02 |
| 268 ## - Previous citation |
|---|
| -- |
Urology. 2020 Aug 15 |
| 269 ## - Original dates |
|---|
| Original fiscal year |
FY2021 |
| 520 ## - SUMMARY, ETC. |
|---|
| Abstract |
METHODS: Using the National Cancer Database, we identified patients with muscle invasive bladder cancer from 2004-2014. Treatments analyzed included no treatment, cystectomy, neoadjuvant chemotherapy plus cystectomy ("optimal treatment"), cystectomy plus adjuvant chemotherapy, and chemoradiation. Propensity matching compared mortality outcomes between sexes. Logistic models evaluated predictors of receiving optimal treatment, as well as mortality. |
| 520 ## - SUMMARY, ETC. |
|---|
| Abstract |
OBJECTIVE: To identify racial and sex disparities in the treatment and outcomes of muscle-invasive bladder cancer (MIBC) using a nationwide oncology outcomes database. |
| 520 ## - SUMMARY, ETC. |
|---|
| Abstract |
RESULTS: 47229 patients were identified. Most patients were male (73.4%) and underwent cystectomy alone (69.0%). Propensity score matching demonstrated increased 90-day mortality in women vs. men (13.0% vs. 11.6%, p=0.009), despite adjusting for differences in treatments between sexes. Logistic regression models showed no difference in receipt of optimal treatment between sexes (OR 1.01, 95% CI 0.83-1.22) although black patients were less likely to receive optimal treatment (OR 0.15, 95% CI 0.05-0.48). Logistic regression models confirmed increased 90-day mortality in female (OR 1.17, CI 1.08-1.27, p<0.001) and black (OR 1.29, CI 1.11-1.50, p=0.001) patients. Females had a lower overall survival on Cox regression analysis (HR 0.92, 95% CI 0.87-0.97) CONCLUSIONS: While there do not appear to be significant treatment disparities between sexes, women experience higher 90-day mortality and lower overall survival. Black patients are less likely to receive optimal treatment and have a higher risk of 90-day mortality. Additional research is needed to determine the variables leading to worse outcomes in females and identify impediments to black patients receiving optimal treatment. Copyright (c) 2020. Published by Elsevier Inc. |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
*Healthcare Disparities |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
*Urinary Bladder Neoplasms/mo [Mortality] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
*Urinary Bladder Neoplasms/th [Therapy] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Aged |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Databases, Factual |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Female |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Humans |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Male |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Neoplasm Invasiveness |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Race Factors |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Sex Factors |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
United States/ep [Epidemiology] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Urinary Bladder Neoplasms/pa [Pathology] |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
|---|
| Institution |
MedStar Health Research Institute |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
|---|
| Institution |
MedStar Washington Hospital Center |
| 656 ## - INDEX TERM--OCCUPATION |
|---|
| Department |
Urology |
| 657 ## - INDEX TERM--FUNCTION |
|---|
| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Local Authors |
Carvalho, Filipe |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Local Authors |
Egan, Jillian |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Local Authors |
Hwang, Jonathan J |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Local Authors |
Krasnow, Ross |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Local Authors |
Lynch, John |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Local Authors |
Marinaro, Jessica |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Local Authors |
Stamatakis, Lambros |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Local Authors |
Zeymo, Alexander |
| 790 ## - Authors |
|---|
| All authors |
Carvalho F, Egan J, Hwang J, Kowalczyk K, Krasnow R, Lynch J, Marinaro J, Stamatakis L, Williams S, Zeymo A |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| DOI |
<a href="https://dx.doi.org/10.1016/j.urology.2020.06.087">https://dx.doi.org/10.1016/j.urology.2020.06.087</a> |
| Public note |
https://dx.doi.org/10.1016/j.urology.2020.06.087 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Journal Article |
| Item type description |
Article |
