Prevention of Perinatal HIV Transmission in an Area of High HIV Prevalence in the United States. (Record no. 5541)

MARC details
000 -LEADER
fixed length control field 03783nam a22006017a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 201006s20212021 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0022-3476
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1016/j.jpeds.2020.09.041 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code S0022-3476(20)31174-4 [pii]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 32971142
245 ## - TITLE STATEMENT
Title Prevention of Perinatal HIV Transmission in an Area of High HIV Prevalence in the United States.
251 ## - Source
Source Journal of Pediatrics. 228:101-109, 2021 01.
252 ## - Abbreviated Source
Abbreviated source J Pediatr. 228:101-109, 2021 01.
252 ## - Abbreviated Source
Former abbreviated source J Pediatr. 2020 Sep 21
253 ## - Journal Name
Journal name The Journal of pediatrics
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2021
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2021
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status aheadofprint
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status ppublish
266 ## - Date added to catalog
Date added to catalog 2020-10-06
268 ## - Previous citation
-- Journal of Pediatrics. 2020 Sep 21
501 ## - WITH NOTE
Local holdings Available online from MWHC library: 1995 - present
520 ## - SUMMARY, ETC.
Abstract CONCLUSION: In an area of high HIV prevalence in the US, a large proportion of low-risk HIV-exposed infants received intrapartum zidovudine and was delivered via cesarean delivery. We also observed missed opportunities for the prevention of perinatal HIV transmission. Copyright (c) 2020 Elsevier Inc. All rights reserved.
520 ## - SUMMARY, ETC.
Abstract OBJECTIVE: To evaluate the uptake of perinatal HIV preventive interventions by risk of perinatal HIV transmission in mother-infant pairs in a high HIV prevalence area in the United States (US).
520 ## - SUMMARY, ETC.
Abstract RESULTS: We analyzed 551 HIV-exposed infants and 542 mothers living with HIV. The majority of mothers received ARVs (95.5%), had HIV RNA <=1,000 copies/mL before delivery (81.9%), and received intrapartum zidovudine (65.5%). The majority of all HIV-exposed infants was low-risk (82.6%) and received postpartum ARVs (98.9%). Among low-risk infants, 53.2% were delivered via cesarean delivery, and 62.9% and 96.5% were administered intrapartum and postpartum zidovudine, respectively. Among high-risk infants, 84.4% were delivered via cesarean delivery, 78.1% received intrapartum zidovudine, and 62.5% received combination ARVs. Nine high-risk infants acquired HIV perinatally.
520 ## - SUMMARY, ETC.
Abstract STUDY DESIGN: This was a retrospective cohort study of mother-infant pairs with perinatal HIV exposure during 2013-2017 managed at a subspecialty pediatric HIV program in Washington, DC. We collected demographics, maternal HIV history, delivery mode, maternal and infant antiretroviral drug (ARV) use, and infant's HIV test results. We compared the uptake of recommended preventive interventions in low-risk (mothers on ARVs with viral suppression) and high-risk (mothers without ARVs or viral suppression) mother-infant pairs using Pearson Chi-square, Fisher exact, Wilcoxon rank sum tests, and logistic regression.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *DNA, Viral/an [Analysis]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *HIV Infections/pc [Prevention & Control]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *HIV/ge [Genetics]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Infectious Disease Transmission, Vertical/pc [Prevention & Control]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Postpartum Period
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Pregnancy Complications, Infectious/ep [Epidemiology]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Adult
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Female
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element HIV Infections/ep [Epidemiology]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Infant, Newborn
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Male
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Pregnancy
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Prevalence
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Prognosis
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Retrospective Studies
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element United States/ep [Epidemiology]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Young Adult
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Health Research Institute
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Scott, Rachel K
790 ## - Authors
All authors Castel AD, Ferrer KT, Griffith CJ, Koay WLA, Manepalli KV, Rakhmanina NY, Scott RK, Zhang J
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1016/j.jpeds.2020.09.041">https://dx.doi.org/10.1016/j.jpeds.2020.09.041</a>
Public note https://dx.doi.org/10.1016/j.jpeds.2020.09.041
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 10/06/2020   32971142 32971142 10/06/2020 10/06/2020 Journal Article

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