Glycogenic Hepatopathy: A Reversible Complication of Uncontrolled Diabetes Mellitus. (Record no. 5654)
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000 -LEADER | |
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fixed length control field | 02356nam a22004097a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 201006s20202020 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
International Standard Serial Number | 2168-8184 |
024 ## - OTHER STANDARD IDENTIFIER | |
Standard number or code | 10.7759/cureus.9323 [doi] |
024 ## - OTHER STANDARD IDENTIFIER | |
Standard number or code | PMC7444849 [pmc] |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
PMID | 32850201 |
245 ## - TITLE STATEMENT | |
Title | Glycogenic Hepatopathy: A Reversible Complication of Uncontrolled Diabetes Mellitus. |
251 ## - Source | |
Source | Cureus. 12(7):e9323, 2020 Jul 21. |
252 ## - Abbreviated Source | |
Abbreviated source | Cureus. 12(7):e9323, 2020 Jul 21. |
253 ## - Journal Name | |
Journal name | Cureus |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Year | 2020 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Manufacturer | FY2021 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] | |
Publication status | epublish |
266 ## - Date added to catalog | |
Date added to catalog | 2020-10-06 |
520 ## - SUMMARY, ETC. | |
Abstract | Glycogenic hepatopathy (GH) is a rare complication of long-standing uncontrolled type I diabetes mellitus (TIDM) resulting in liver dysfunction and hepatomegaly due to intrahepatic deposition of glycogen. Herein we present a 19-year-old male with a history of TIDM and multiple prior hospitalizations with diabetic ketoacidosis (DKA) who presented with nausea, vomiting, right upper quadrant pain, and massive hepatomegaly. Laboratory workup was consistent with DKA and revealed a greater than 10-fold increase in liver enzymes. Despite the resolution of DKA, his liver function was worsening, and further workup was indicated. Ultimately, he underwent a liver biopsy that showed swollen hepatocytes overloaded with intracytoplasmic glycogen consistent with glycogenic hepatopathy. It is an underestimated entity and physicians should have a high index of suspicion for GH in individuals presenting with liver dysfunction, hepatomegaly, and poor glycemic control in TIDM. Strict glycemic control may result in complete resolution of disease. Copyright (c) 2020, Yousaf et al. |
546 ## - LANGUAGE NOTE | |
Language note | English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | IN PROCESS -- NOT YET INDEXED |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME | |
Institution | MedStar Franklin Square Medical Center |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME | |
Institution | MedStar Good Samaritan Hospital |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME | |
Institution | MedStar Harbor Hospital |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME | |
Institution | MedStar Union Memorial Hospital |
656 ## - INDEX TERM--OCCUPATION | |
Department | Internal Medicine |
657 ## - INDEX TERM--FUNCTION | |
Medline publication type | Case Reports |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Local Authors | Chaudhary, Fizah |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Local Authors | Ehsan, Hamid |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Local Authors | Sagheer, Usman |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Local Authors | Yousaf, Muhammad N |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Local Authors | Yousaf, Muhammad N |
790 ## - Authors | |
All authors | Chaudhary F, Ehsan H, Ehsan S, Sagheer U, Yousaf MN |
856 ## - ELECTRONIC LOCATION AND ACCESS | |
DOI | <a href="https://dx.doi.org/10.7759/cureus.9323">https://dx.doi.org/10.7759/cureus.9323</a> |
Public note | https://dx.doi.org/10.7759/cureus.9323 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Koha item type | Journal Article |
Item type description | Article |
Withdrawn status | Lost status | Damaged status | Not for loan | Collection | Home library | Current library | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
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MedStar Authors Catalog | MedStar Authors Catalog | 10/06/2020 | 32850201 | 32850201 | 10/06/2020 | 10/06/2020 | Journal Article |