Role of colonoscopy in diagnosis of capecitabine associated ileitis: Two case reports. (Record no. 5705)

MARC details
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fixed length control field 02154nam a22003497a 4500
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fixed length control field 201229s20192019 xxu||||| |||| 00| 0 eng d
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Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 31205599
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Title Role of colonoscopy in diagnosis of capecitabine associated ileitis: Two case reports.
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Source World Journal of Gastrointestinal Endoscopy. 11(5):383-388, 2019 May 16.
252 ## - Abbreviated Source
Abbreviated source World J Gastrointest Endosc. 11(5):383-388, 2019 May 16.
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Journal name World journal of gastrointestinal endoscopy
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Year 2019
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Manufacturer FY2019
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Publication status ppublish
266 ## - Date added to catalog
Date added to catalog 2020-12-29
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: Capecitabine is considered a first line agent in adjuvant therapy for breast and colorectal cancer. However, cases of severe diarrhea have been reported with increasing frequency in recent years. When diarrhea is severe and prolonged, capecitabine associated ileitis should be considered as a possible etiology.
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Abstract CASE SUMMARY: Herein, we present two cases of capecitabine ileitis, specifically involving the terminal ileum and ascending colon. We will demonstrate the disease course and treatment modalities applied to alleviate this condition, as well as discuss the merits of using colonoscopy to aid in diagnosis.
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Abstract CONCLUSION: Ultimately our cases demonstrate that symptomatic management with traditional anti-diarrheal medications is largely ineffective. Prompt recognition and discontinuation of capecitabine is an imperative step in proper management of this condition and colonoscopy with biopsy can be helpful when the diagnosis is unclear.
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Language note English
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Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
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Institution MedStar Washington Hospital Center
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Department Gastroenterology
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Department Medicine/Internal Medicine
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Medline publication type Case Reports
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Local Authors Dao, Alexander
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Local Authors Mandaliya, Rohan
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Local Authors Nakshabandi, Ahmad
790 ## - Authors
All authors Charabaty A, Dao AE, Hsu A, Mandaliya R, Mattar M, Nadella S, Nakshabandi A, Sivaraman A
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DOI <a href="https://dx.doi.org/10.4253/wjge.v11.i5.383">https://dx.doi.org/10.4253/wjge.v11.i5.383</a>
Public note https://dx.doi.org/10.4253/wjge.v11.i5.383
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
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          MedStar Authors Catalog MedStar Authors Catalog 12/29/2020   31205599 31205599 12/29/2020 12/29/2020 Journal Article

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