MARC details
| 000 -LEADER |
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| fixed length control field |
03210nam a22004217a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
210607s20212021 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
1083-7159 |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1002/onco.13690 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
PMC8018328 [pmc] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
33512741 |
| 245 ## - TITLE STATEMENT |
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| Title |
Does Scalp Cooling Have the Same Efficacy in Black Patients Receiving Chemotherapy for Breast Cancer?. |
| 251 ## - Source |
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| Source |
Oncologist. 26(4):292-e548, 2021 04. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
Oncologist. 26(4):292-e548, 2021 04. |
| 253 ## - Journal Name |
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| Journal name |
The oncologist |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2021 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2021 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
ppublish |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2021-02-17 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
BACKGROUND: The Paxman scalp cooling (SC) device is U.S. Food and Drug Administration (FDA)-approved for prevention of chemotherapy-induced alopecia. Studies report 50%-80% success rates and high patient satisfaction, yet there have been no studies of SC in Black patients. We conducted a phase II feasibility study of Paxman SC with a planned enrollment of 30 Black patients receiving chemotherapy for stage I-III breast cancer. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSION: SC may not be efficacious in preventing alopecia in Black women. Differences in hair thickness, hair volume, and limitations of cooling cap design are possible contributing factors. Copyright (c) AlphaMed Press; the data published online to support this summary are the property of the authors. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
LESSONS LEARNED: Despite U.S. Food and Drug Administration approval to reduce alopecia, data on efficacy of scalp cooling in Black patients with cancer are limited by lack of minority representation in prior clinical trials. Scalp cooling devices may have less efficacy in Black patients; additional studies are required to explore the possible causes for this, including hair texture and cap design. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
METHODS: Black patients who planned to receive at least four cycles of chemotherapy with non-anthracycline (NAC) or anthracycline (AC) regimens were eligible. Alopecia was assessed by trained oncology providers using the modified Dean scale (MDS) prior to each chemotherapy session. Distress related to alopecia was measured by the Chemotherapy Alopecia Distress Scale (CADS). |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
RESULTS: Fifteen patients enrolled in the intervention before the study was closed early because of lack of efficacy. Median MDS and CADS increased after SC, suggesting increased hair loss (p < .001) and alopecia distress (p = .04). Only one participant was successful in preventing significant hair loss; the majority stopped SC before chemotherapy completion because of grade 3 alopecia (>50% hair loss). |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Health Research Institute |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
Washington Cancer Institute |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Alintah, Princess |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Chitalia, Ami |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Dilawari, Asma |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Gallagher, Christopher |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Tiwari, Shruti |
| 790 ## - Authors |
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| All authors |
Adams-Campbell L, Alintah P, Chitalia A, Dash C, Dilawari A, Gallagher C, Paxman R, Tiwari S |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1002/onco.13690">https://dx.doi.org/10.1002/onco.13690</a> |
| Public note |
https://dx.doi.org/10.1002/onco.13690 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
