MARC details
| 000 -LEADER |
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| fixed length control field |
03247nam a22003737a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
210217s20212021 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
0148-396X |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1093/neuros/nyaa530 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
6096357 [pii] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
33442725 |
| 245 ## - TITLE STATEMENT |
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| Title |
The Use of Antiplatelet Agents and Heparin in the 24-Hour Postintravenous Alteplase Window for Neurointervention. |
| 251 ## - Source |
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| Source |
Neurosurgery. 2021 Jan 13 |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
Neurosurgery. 2021 Jan 13 |
| 253 ## - Journal Name |
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| Journal name |
Neurosurgery |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2021 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2021 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
aheadofprint |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2021-02-17 |
| 501 ## - WITH NOTE |
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| Local holdings |
Available online from MWHC library: 1992 - present, Available in print through MWHC library: 1999 - 2006 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
BACKGROUND: Intravenous (IV) alteplase with mechanical thrombectomy has been found to be superior to alteplase alone in select patients with intracranial large vessel occlusion. Current guidelines discourage the use of antiplatelet agents or heparin for 24 h following alteplase. However, their use is often necessary in certain circumstances during thrombectomy procedures. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSION: The use of antiplatelet agents and heparin for stroke interventions following IV alteplase appears to be safe without significant increased risk of hemorrhagic complications in this group of patients when compared to control data and randomized controlled trials. Copyright (c) Congress of Neurological Surgeons 2021. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
METHODS: This is a multicenter retrospective review of the use of antiplatelet agents and/or heparin in patients within 24 h following tPA administration. Patient demographics, comorbidities, bleeding complications, and discharge outcomes were collected. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
OBJECTIVE: To study the safety and outcomes in patients who received blood thinning medications for thrombectomy after IV Tissue-Type plasminogen activator (tPA). |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
RESULTS: A series of 88 patients at 9 centers received antiplatelet medications and/or heparin anticoagulation following IV alteplase for revascularization procedures requiring stenting. The mean National Institutes of Health Stroke Scale (NIHSS) on admission was 14.6. Reasons for use of a stent included internal carotid artery occlusion in 74% of patients. Thrombolysis in cerebral infarction (TICI) 2b-3 revascularization was accomplished in 90% of patients. The rate of symptomatic intracranial hemorrhage (sICH) was 8%; this was not significantly different than the sICH rate for a matched group of patients not receiving antiplatelets or heparin during the same time frame. Functional independence at 90 d (modified Rankin Scale 0-2) was seen in 57.8% of patients. All-cause mortality was 12%. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Medical Group |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Felbaum, Daniel R |
| 790 ## - Authors |
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| All authors |
Arthur A, Binning MJ, Crowley RW, Daou BJ, Felbaum DR, Goyal N, Levy E, Liebman KM, Maxwell CR, McAree M, Pandey AS, Rai HH, Ringer AJ, Tawk RG, Tschoe C, Vakharia K, Veznedaroglu E, Wolfe SQ |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1093/neuros/nyaa530">https://dx.doi.org/10.1093/neuros/nyaa530</a> |
| Public note |
https://dx.doi.org/10.1093/neuros/nyaa530 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
