MARC details
000 -LEADER |
fixed length control field |
03200nam a22003737a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
210217s20202020 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
2155-384X |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
01720094-202012000-00020 [pii] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.14309/ctg.0000000000000283 [doi] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
PMC7743841 [pmc] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
33464001 |
245 ## - TITLE STATEMENT |
Title |
Assessment of Weight Loss and Gastrointestinal Symptoms Suggestive of Exocrine Pancreatic Dysfunction After Acute Pancreatitis. |
251 ## - Source |
Source |
Clinical and Translational Gastroenterology. 11(12):e00283, 2020 Dec 15. |
252 ## - Abbreviated Source |
Abbreviated source |
Clin Transl Gastroenterol. 11(12):e00283, 2020 Dec 15. |
253 ## - Journal Name |
Journal name |
Clinical and translational gastroenterology |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2020 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2021 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
epublish |
266 ## - Date added to catalog |
Date added to catalog |
2021-02-17 |
520 ## - SUMMARY, ETC. |
Abstract |
DISCUSSION: Weight loss after AP occurs in one-quarter of patients and is associated with AP severity. EPD incidence after AP is likely underappreciated. Further work is needed to assess EPD and potential for pancreatic enzyme supplementation. Copyright (c) 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. |
520 ## - SUMMARY, ETC. |
Abstract |
INTRODUCTION: Studies evaluating the natural history of exocrine pancreatic dysfunction (EPD) after acute pancreatitis (AP) are sparse. This study aims to assess incidence and predictors of weight loss and gastrointestinal (GI) symptoms suggestive of EPD 12 months after an AP episode. |
520 ## - SUMMARY, ETC. |
Abstract |
METHODS: Patients enrolled in the Pancreatitis-associated Risk of Organ Failure Study at the time of an AP episode were included. Weight and GI symptom data were prospectively collected by self-report at enrollment and at 3- and 12-month (windows 2-7 and 8-20) telephone follow-ups. Multivariable logistic regression was used to assess factors associated with >=10% total body weight loss (EPD surrogate) at 12 months. A generalized estimating equation was used to measure each factor's population effect (in pounds) over 12 months after AP. |
520 ## - SUMMARY, ETC. |
Abstract |
RESULTS: Follow-up at 12 months in 186 patients (median age = 54 years, 46% men, 45% biliary, 65% first AP attack) revealed weight loss >=10% from baseline, occurring in 44 patients (24%). Risk of weight loss increased with higher baseline body mass index, previous diagnosis of diabetes mellitus, and worsening AP severity (all P < 0.010). GI symptoms were reported in 13/31 (42%) patients at 12 months. AP severity was independently associated with >=10% weight loss at 12 months. Over 12 months, men lost more weight than women (average 9.5 lbs); patients with severe AP lost, on average, 14 lbs. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Washington Hospital Center |
656 ## - INDEX TERM--OCCUPATION |
Department |
Medicine/General Internal Medicine |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Pothoulakis, Ioannis |
790 ## - Authors |
All authors |
Greer PJ, Harb D, Komara N, Koutroumpakis F, Lahooti A, Mays M, Ooka K, Papachristou GI, Paragomi P, Phillips AE, Pothoulakis I, Stello K, Whitcomb DC |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.14309/ctg.0000000000000283">https://dx.doi.org/10.14309/ctg.0000000000000283</a> |
Public note |
https://dx.doi.org/10.14309/ctg.0000000000000283 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |