Safety and efficacy of sofosbuvir/velpatasvir/voxilaprevir in post-liver transplant patients with previous direct-acting antiviral failure: Six case reports. (Record no. 6112)

MARC details
000 -LEADER
fixed length control field 02423nam a22003617a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 210217s20202020 xxu||||| |||| 00| 0 eng d
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.4254/wjh.v12.i12.1341 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code PMC7772723 [pmc]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 33442459
245 ## - TITLE STATEMENT
Title Safety and efficacy of sofosbuvir/velpatasvir/voxilaprevir in post-liver transplant patients with previous direct-acting antiviral failure: Six case reports.
251 ## - Source
Source World Journal of Hepatology. 12(12):1341-1348, 2020 Dec 27.
252 ## - Abbreviated Source
Abbreviated source World J Hepatol. 12(12):1341-1348, 2020 Dec 27.
253 ## - Journal Name
Journal name World journal of hepatology
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2020
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2021
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status ppublish
266 ## - Date added to catalog
Date added to catalog 2021-02-17
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: Direct-acting antiviral (DAA) therapy regimens are highly effective at eliminating hepatitis C virus (HCV) infection but rates of sustained virologic response (SVR) are lower in patients with decompensated cirrhosis or hepatocellular carcinoma. Since many of these patients will be referred for liver transplant, they will require retreatment after transplantation. Sofosbuvir/velpatasvir/voxilaprevir (SOF/VEL/VOX) is recommended by guidelines as the preferred regimen to treat HCV in DAA-experienced patients following liver transplant however there is limited data.
520 ## - SUMMARY, ETC.
Abstract CASE SUMMARY: We present the cases of six liver transplant recipients who had previous treatment failure with sofosbuvir-based DAA therapy prior to transplantation and who then received SOF/VEL/VOX after transplant.
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Abstract CONCLUSION: This case series demonstrate the real-world efficacy and safety of SOF/VEL/VOX in the post liver transplant setting. Treatment was successful with all patients achieving SVR, it was well tolerated, and there were minimal drug-drug interactions with their immunosuppressants. Copyright (c)The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Medical Group
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Washington Hospital Center
656 ## - INDEX TERM--OCCUPATION
Department Transplant Hepatology Service
657 ## - INDEX TERM--FUNCTION
Medline publication type Case Reports
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Higley, Cory
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Lalos, Alexander
790 ## - Authors
All authors Higley C, Hsu CC, Lalos AT, Nadella S, Smith C
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.4254/wjh.v12.i12.1341">https://dx.doi.org/10.4254/wjh.v12.i12.1341</a>
Public note https://dx.doi.org/10.4254/wjh.v12.i12.1341
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 02/17/2021   33442459 33442459 02/17/2021 02/17/2021 Journal Article

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