MARC details
000 -LEADER |
fixed length control field |
02423nam a22003617a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
210217s20202020 xxu||||| |||| 00| 0 eng d |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.4254/wjh.v12.i12.1341 [doi] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
PMC7772723 [pmc] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
33442459 |
245 ## - TITLE STATEMENT |
Title |
Safety and efficacy of sofosbuvir/velpatasvir/voxilaprevir in post-liver transplant patients with previous direct-acting antiviral failure: Six case reports. |
251 ## - Source |
Source |
World Journal of Hepatology. 12(12):1341-1348, 2020 Dec 27. |
252 ## - Abbreviated Source |
Abbreviated source |
World J Hepatol. 12(12):1341-1348, 2020 Dec 27. |
253 ## - Journal Name |
Journal name |
World journal of hepatology |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2020 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2021 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
ppublish |
266 ## - Date added to catalog |
Date added to catalog |
2021-02-17 |
520 ## - SUMMARY, ETC. |
Abstract |
BACKGROUND: Direct-acting antiviral (DAA) therapy regimens are highly effective at eliminating hepatitis C virus (HCV) infection but rates of sustained virologic response (SVR) are lower in patients with decompensated cirrhosis or hepatocellular carcinoma. Since many of these patients will be referred for liver transplant, they will require retreatment after transplantation. Sofosbuvir/velpatasvir/voxilaprevir (SOF/VEL/VOX) is recommended by guidelines as the preferred regimen to treat HCV in DAA-experienced patients following liver transplant however there is limited data. |
520 ## - SUMMARY, ETC. |
Abstract |
CASE SUMMARY: We present the cases of six liver transplant recipients who had previous treatment failure with sofosbuvir-based DAA therapy prior to transplantation and who then received SOF/VEL/VOX after transplant. |
520 ## - SUMMARY, ETC. |
Abstract |
CONCLUSION: This case series demonstrate the real-world efficacy and safety of SOF/VEL/VOX in the post liver transplant setting. Treatment was successful with all patients achieving SVR, it was well tolerated, and there were minimal drug-drug interactions with their immunosuppressants. Copyright (c)The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Medical Group |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Washington Hospital Center |
656 ## - INDEX TERM--OCCUPATION |
Department |
Transplant Hepatology Service |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Case Reports |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Higley, Cory |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Lalos, Alexander |
790 ## - Authors |
All authors |
Higley C, Hsu CC, Lalos AT, Nadella S, Smith C |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.4254/wjh.v12.i12.1341">https://dx.doi.org/10.4254/wjh.v12.i12.1341</a> |
Public note |
https://dx.doi.org/10.4254/wjh.v12.i12.1341 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |