Multiparameter diagnostic sensor measurements during clinically stable periods and worsening heart failure in ambulatory patients. (Record no. 6204)

MARC details
000 -LEADER
fixed length control field 03431nam a22003377a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 210607s20212021 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 2055-5822
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1002/ehf2.13261 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code PMC8006698 [pmc]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 33619893
245 ## - TITLE STATEMENT
Title Multiparameter diagnostic sensor measurements during clinically stable periods and worsening heart failure in ambulatory patients.
251 ## - Source
Source ESC heart failure. 8(2):1571-1581, 2021 Apr.
252 ## - Abbreviated Source
Abbreviated source ESC Heart Fail. 8(2):1571-1581, 2021 Apr.
253 ## - Journal Name
Journal name ESC heart failure
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2021
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2021
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status ppublish
266 ## - Date added to catalog
Date added to catalog 2021-03-10
520 ## - SUMMARY, ETC.
Abstract AIMS: This study aims to characterize the range of implantable device-based sensor values including heart sounds, markers of ventilation, thoracic impedance, activity, and heart rate for patients with heart failure (HF) when patients were deemed to be in clinically stable periods against the time course of acute decompensation and recovery from HF events.
520 ## - SUMMARY, ETC.
Abstract CONCLUSIONS: Device-based physiologic sensors not only revealed progressive worsening leading up to HF events but also differentiated patients at increased risk of HF events when presumed to be clinically stable. Copyright (c) 2021 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.
520 ## - SUMMARY, ETC.
Abstract METHODS AND RESULTS: The MultiSENSE trial followed 900 patients implanted with a COGNIS CRT-D for up to 1 year. Chronic, ambulatory diagnostic sensor data were collected and evaluated during clinically stable periods (CSP: unchanged NYHA classification, no adverse events, and weight change <=2.27 kg), and in the timeframe leading up to and following HF events (HF admissions or unscheduled visits with intravenous HF treatment). Physiologic sensor data from 1667 CSPs occurring in 676 patients were compared with those data leading up to and following 192 HF events in 106 patients. Overall, the mean age was 66.6 years, and the population were predominantly male (73%). Patients were primarily in NYHA II (67%), with a mean LVEF of 29.6% and median NT-proBNP of 754.5 pg/mL. Sensor values during CSP were poorer in patients who had HF events during the study period than those without HF events, including first heart sound (S1: 2.18 +/- 0.84 mG vs. 2.62 +/- 0.95 mG, P = 0.002), third heart sound (S3: 1.13 +/- 0.36 mG vs. 0.91 +/- 0.30 mG, P < 0.001), thoracic impedance (45.66 +/- 8.78 Ohm vs. 50.33 +/- 8.43 Ohm, P < 0.001), respiratory rate (19.09 +/- 3.10 br/min vs. 17.66 +/- 2.39 br/min, P = 0.002), night time heart rate (73.39 +/- 8.36 b.p.m. vs. 69.56 +/- 8.09 b.p.m., P = 0.001), patient activity (1.69 +/- 1.84 h vs. 2.56 +/- 2.20 h, P = 0.006), and HeartLogic index (11.07 +/- 12.14 vs. 5.31 +/- 5.13, P = 0.001). Sensor parameters measured worsening status leading up to HF events with recovery of values following treatment.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Heart & Vascular Institute
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Eldadah, Zayd A
790 ## - Authors
All authors An Q, Averina V, Boehmer JP, Duray GZ, Eldadah Z, Ferrick K, Gardner RS, Hammill EF, Nair DG, Sriratanasathavorn C, Stancak B, Thakur P, Wariar R, Zhang Y
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1002/ehf2.13261">https://dx.doi.org/10.1002/ehf2.13261</a>
Public note https://dx.doi.org/10.1002/ehf2.13261
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 03/10/2021   33619893 33619893 03/10/2021 03/10/2021 Journal Article

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