MARC details
000 -LEADER |
fixed length control field |
03431nam a22003377a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
210607s20212021 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
2055-5822 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1002/ehf2.13261 [doi] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
PMC8006698 [pmc] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
33619893 |
245 ## - TITLE STATEMENT |
Title |
Multiparameter diagnostic sensor measurements during clinically stable periods and worsening heart failure in ambulatory patients. |
251 ## - Source |
Source |
ESC heart failure. 8(2):1571-1581, 2021 Apr. |
252 ## - Abbreviated Source |
Abbreviated source |
ESC Heart Fail. 8(2):1571-1581, 2021 Apr. |
253 ## - Journal Name |
Journal name |
ESC heart failure |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2021 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2021 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
ppublish |
266 ## - Date added to catalog |
Date added to catalog |
2021-03-10 |
520 ## - SUMMARY, ETC. |
Abstract |
AIMS: This study aims to characterize the range of implantable device-based sensor values including heart sounds, markers of ventilation, thoracic impedance, activity, and heart rate for patients with heart failure (HF) when patients were deemed to be in clinically stable periods against the time course of acute decompensation and recovery from HF events. |
520 ## - SUMMARY, ETC. |
Abstract |
CONCLUSIONS: Device-based physiologic sensors not only revealed progressive worsening leading up to HF events but also differentiated patients at increased risk of HF events when presumed to be clinically stable. Copyright (c) 2021 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. |
520 ## - SUMMARY, ETC. |
Abstract |
METHODS AND RESULTS: The MultiSENSE trial followed 900 patients implanted with a COGNIS CRT-D for up to 1 year. Chronic, ambulatory diagnostic sensor data were collected and evaluated during clinically stable periods (CSP: unchanged NYHA classification, no adverse events, and weight change <=2.27 kg), and in the timeframe leading up to and following HF events (HF admissions or unscheduled visits with intravenous HF treatment). Physiologic sensor data from 1667 CSPs occurring in 676 patients were compared with those data leading up to and following 192 HF events in 106 patients. Overall, the mean age was 66.6 years, and the population were predominantly male (73%). Patients were primarily in NYHA II (67%), with a mean LVEF of 29.6% and median NT-proBNP of 754.5 pg/mL. Sensor values during CSP were poorer in patients who had HF events during the study period than those without HF events, including first heart sound (S1: 2.18 +/- 0.84 mG vs. 2.62 +/- 0.95 mG, P = 0.002), third heart sound (S3: 1.13 +/- 0.36 mG vs. 0.91 +/- 0.30 mG, P < 0.001), thoracic impedance (45.66 +/- 8.78 Ohm vs. 50.33 +/- 8.43 Ohm, P < 0.001), respiratory rate (19.09 +/- 3.10 br/min vs. 17.66 +/- 2.39 br/min, P = 0.002), night time heart rate (73.39 +/- 8.36 b.p.m. vs. 69.56 +/- 8.09 b.p.m., P = 0.001), patient activity (1.69 +/- 1.84 h vs. 2.56 +/- 2.20 h, P = 0.006), and HeartLogic index (11.07 +/- 12.14 vs. 5.31 +/- 5.13, P = 0.001). Sensor parameters measured worsening status leading up to HF events with recovery of values following treatment. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Heart & Vascular Institute |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Eldadah, Zayd A |
790 ## - Authors |
All authors |
An Q, Averina V, Boehmer JP, Duray GZ, Eldadah Z, Ferrick K, Gardner RS, Hammill EF, Nair DG, Sriratanasathavorn C, Stancak B, Thakur P, Wariar R, Zhang Y |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1002/ehf2.13261">https://dx.doi.org/10.1002/ehf2.13261</a> |
Public note |
https://dx.doi.org/10.1002/ehf2.13261 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |